The article "Public, Private Health Concerns Spur Rapid Progress In Toxicology" (The Scientist, Feb. 17, 1992, page 1) did not mention the significant role that the public's concern for animals has had in advancing in vitro toxicology. This concern, for example, led to the establishment of the Center for Alternatives to Animal Testing at Johns Hopkins University in 1981. In fact, one of the toxicologists quoted in the article--John Frazier--is the associate director of that center (in addition to his position cited in the article). No survey of the positive influences on the science of toxicology would be complete without reference to public pressure to develop alternatives to the use of animals.

Vice President
Laboratory Animals
The Humane Society of the United States
Washington, D.C.

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