Ahuman cell map is vital information for researchers designing immunotherapies. To create these maps, scientists use techniques such as flow cytometry and RNA sequencing to characterize immune cells based on their physical properties. However, researchers have identified numerous cells with identical surface marker phenotypes that show vast functional diversity, highlighting a gap between the information provided by these traditional techniques and the ability to characterize cell function.
Immune Therapy Advancement with IsoPlexis "Functional Phenotyping"
IsoPlexis’ single-cell functional proteomics platform fills this gap by providing a more complete picture of how individual cell functionality provides critical information missing from genotypes and marker expression through “functional phenotyping.” The platform can identify functional differences in phenotypically identical cells and characterize and measure cytokine secretion in single cells. This allows scientists to uncover unique polyfunctional cellular subsets that can produce multiple cytokines simultaneously. This technology has advanced cancer immunology research and development of immune ...
