Just What Is Synthetic Biology?

FEATUREIs This Life?Just What Is Synthetic Biology? The term "synthetic biology" appears in the title of a 1913Nature article but then disappears until the 1980s, at which pointits use seems interchangeable with recombinant DNA technology.today, the term is used to describe the wholesale engineering of geneticcircuits, entire genomes, and even organisms and has appea

Written byJack Lucentini
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

The term "synthetic biology" appears in the title of a 1913Nature article but then disappears until the 1980s, at which pointits use seems interchangeable with recombinant DNA technology.today, the term is used to describe the wholesale engineering of geneticcircuits, entire genomes, and even organisms and has appeared in nearly50 papers since 2000. nevertheless, the definition remains elusive.Here's what some of the field's practitioners said when asked,"What is synthetic biology?"

"Synthetic biology is doing with biology what we've done with electricalengineering, what chemical engineering has done for chemistry."

-Jay Keasling, professor of chemical engineering,University of California, Berkeley

"The lines between synthetic biology and classical recombinant DNAtechniques are still blurred. Basically it's taking those elements to thenext level - actually engineering the cell."

-Robert Holt, head of sequencing, Genome Sciences Center,British Columbia Cancer Research Center

"The main issue is separating synthetic biology from existing fields likegenetic engineering or cellular engineering. It's treating ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH