Since its launch, we have fulfilled more than 3,500 requests for downloads and hard copies. In this latest edition, we offer two new chapters.
Optimization and characterization of neuronal and neuroimmune cell models, especially human iPSC-derived models, continues to be a focus for cellular neuroscientists in search of relevant disease models. In Kinetic Assays for Studying Neuronal Cell Models, we describe a suite of assays that enable study of cellular structure and function. “This chapter showcases data ranging from chemotactic movement and phagocytic activity of microglia to long term measurements of neuronal activity,” said Kimberly Wicklund, Ph.D., Head of Product Management for IncuCyte® at Sartorius Corporation. “Of particular interest for those developing neuronal disease models is our new neuronal activity assay. With our unique patent-pending technology, we can quantify when neurons become active and form connected networks over weeks or even months in 96-well plates, all while the cells stay ...