
Spring 2023
The Cancer Code
Once dismissed as genomic noise, some noncoding sequences (and the microproteins they encode) play important roles in cancer
Features
Speaking of Science

Ten Minute Sabbatical
Take a break from the bench to puzzle and peruse
Critic at Large

Opinion: New Diabetes Drug Signals Shift to Preventing Autoimmunity
A therapy for type 1 diabetes is the first to treat patients before symptoms appear, paving the way toward preventing this and other autoimmune diseases.
The Literature

How Tadpoles Garner the Energy to Regenerate Their Tails
A metabolic pathway used for tail regrowth may be critical for tissue regeneration in some cells, a study suggests.
Notebook

Researchers Watch Fish Rot, for Science
Recording the pH within decaying organs for the first time, researchers come closer to understanding why some soft tissues are more likely to be preserved as fossils than others.

Ecologists Use Museum Specimens to Dig into the Parasitic Past
New techniques to quantify what lived in and on preserved animals throw light on how parasite abundance has changed over time.
Scientist to Watch

Alex Muir Explores Cancer Cells’ Menu
The University of Chicago cell biologist is studying how the nutrients available to cancers influence their growth.
Careers

How Do Scientists Decide a Species Has Gone Extinct?
Getting it wrong can harm the very creatures that scientists are trying to protect.
Reading Frames

The Skin Battery
The “wound current” has intrigued scientists for more than a century. It could turn out to be the key to healing catastrophic injuries.
Foundations

Bathing Through the Ages: 1300–1848
Public bathing, ubiquitous around the world and through the ages, plays an often-unappreciated role in public health.
Infographics

Infographic: Transposable elements in cancer
Jumping genes are let loose in cancerous cells, with multiple effects on cell health.

Infographic: How Tadpoles Use Glucose to Fuel Tail Regrowth
Unlike other fast-growing cells, regenerating tadpole cells fuel growth using the pentose phosphate pathway rather than glycolysis, a study indicates.













