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DNA molecule inside the living cell

Spring 2023

The Cancer Code

Once dismissed as genomic noise, some noncoding sequences (and the microproteins they encode) play important roles in cancer

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Features

Artists' renditions of cancer cells and tRNA molecules superimposed over one another.

Long noncoding RNAs and Microproteins Can Spark Cancer—or Sometimes Squelch It

Composite image showing genes radiating from tumor cells

Jumping Genes’ Role in Cancer

Speaking of Science

Crossword article image

Ten Minute Sabbatical

Critic at Large

Illustration of woman looking at floating cells through a telescope

Opinion: New Diabetes Drug Signals Shift to Preventing Autoimmunity

The Literature

Tadpole

How Tadpoles Garner the Energy to Regenerate Their Tails

Notebook

Thomas Clements dissects fish

Researchers Watch Fish Rot, for Science

A monogenean flatworm

Ecologists Use Museum Specimens to Dig into the Parasitic Past

Scientist to Watch

Portrait of Alex Muir

Alex Muir Explores Cancer Cells’ Menu

Careers

A male and female Chiriqui harlequin frog (<em>Atelopus chiriquiensis</em>) photographed in 2010. The species was declared extinct in 2019.

How Do Scientists Decide a Species Has Gone Extinct?

Reading Frames

<em>We are Electric</em> book cover

The Skin Battery

Foundations

In urban bathhouses in Germany and the surrounding low countries, bathhouse proprietors, known as baders, provided visitors with basic medical care. To draw blood, baders would scratch the skin before placing a heated cupping glass over the incision to extract blood and purge the body. Other tools associated with baders, including dental forceps and an amputation saw, hint at further services they provided.

Bathing Through the Ages: 1300–1848

Infographics

Infographic showing transposable elements in cancer

Infographic: Transposable elements in cancer

Infographic showing the process of tail regeneration in tadpoles

Infographic: How Tadpoles Use Glucose to Fuel Tail Regrowth

August 2026 Digest cover
August 2026

Epic Fail: Sea-Monkeys Sabotage Fieldwork

When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.

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Overcoming Immunotherapy Resistance in Liver Cancer

Overcoming Immunotherapy Resistance in Liver Cancer

Axion Biosystems
Optimizing NGS Library Preparation for Reliable Sequencing Data

Optimizing NGS Library Preparation for Reliable Sequencing Data

Covaris
Using TCR Repertoire Sequencing to Advance Immunology Research

Using TCR Repertoire Sequencing to Advance Immunology Research

Miltenyi
Mapping Clonal Mosaicism in Aging Tissues

Mapping Clonal Mosaicism in Aging Tissues

Mission bio

Products

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Sino Biological Launches SuperNuclease ® Pro with Free Trial Program

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Sino Biological Launches Precisely Characterized Full-Length p-Tau217 Protein to Advance Next-Generation Alzheimer’s Biomarker Assay Development

A photo of a scientist placing the Resipher device on a 96-well plate.

Resipher: Continuous Live-Cell Mitochondrial Respiration Monitoring in 96-Well Plates

Lucid Scientific logo
Conceptual image of ice and frost.

The VAULT100 PRO: Inside the most advanced Stirling Ultracold ULT freezer ever built.

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