The parallel development of instrument hardware and dyes expands the number of overall parameters that can be analyzed in single experimental run, with each additional parameter translating into an exponential increase in data acquisition capacity and research potential. Thanks to over 45 years of development, flow cytometry is now an integral protein analysis tool that enables scientists to delve progressively deeper into cellular characterization and profiling.
As the new millennium began, flow cytometry had reached a plateau, as scientists could not detect more than 18 parameters simultaneously. Around this time, Sirigen designed and optimized a novel class of dyes derived from the chemistry behind Alan Heeger, Alan MacDiarmid, and Hideki Shirakawa’s Nobel Prize-winning discovery of conductive polymers. These new polymer-based dyes were groundbreaking and led initially to a series of direct and energy transfer tandem dyes excited by the violet laser.
Researchers from BD Biosciences recognized the untapped potential of ...
