Manipulating Mouse Memory

Researchers deliver bursts of light to specific cells in the mouse hippocampus to implant false memories about a fearful event.

| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

Mouse hippocampus revealed with the Brainbow techniqueTamily Weissman

Eyewitness testimony has long been an important part of most judicial systems around the world. However, over the last three decades, psychologists have consistently proven how tenuous the memories truly are, and how easily they can be altered or even manufactured through the power of suggestion. Today (July 25), research published in Science provides the first clues regarding the mechanism for creating such faux memories in the brain, demonstrating that the manipulation of a specific subset of neurons in the mouse hippocampus can cause the animals to falsely remember a fear of a foot schock.

“[This] is a very striking investigation that provides clues about the neurobiological mechanisms that may underlie how we acquire false memories,” said Howard Eichenbaum, a neuroscientist at Boston University, who ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • Chris Palmer

    This person does not yet have a bio.
Share
May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo
Characterizing Immune Memory to COVID-19 Vaccination

Characterizing Immune Memory to COVID-19 Vaccination

10X Genomics

Products

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

iStock

Agilent BioTek Cytation C10 Confocal Imaging Reader

agilent technologies logo