Infographic: Reverse Signaling Between Neurons
Infographic: Reverse Signaling Between Neurons
So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.
Infographic: Reverse Signaling Between Neurons
Infographic: Reverse Signaling Between Neurons

So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.

So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.

hippocampus
Hippocampal Cell Communication Is Bidirectional: Study
Hippocampal Cell Communication Is Bidirectional: Study
Christie Wilcox | Jun 4, 2021
In an unexpected twist in neuroscience dogma, the cells on the receiving end of neurotransmission appear to be able to release glutamate to regulate the transmitting cell’s activity.
Opinion: The Overlooked Power of Inhibitory Neurons
Opinion: The Overlooked Power of Inhibitory Neurons
Lauren Aguirre | Jun 1, 2021
Understanding how the brain coordinates electrical activity could be key to developing more-effective treatments for a variety of brain disorders.
New Role for Leptin: Promoting Synapse Formation in Rat Neurons
New Role for Leptin: Promoting Synapse Formation in Rat Neurons
Abby Olena | May 20, 2021
The hormone, which is well known for regulating appetite, appears to influence neuronal development—a finding that could shed light on disorders such as autism that involve dysfunctional synapse formation.
The Neuroscience of Motherhood
The Neuroscience of Motherhood
The Scientist Creative Services Team | Apr 27, 2021
Robert Froemke and Liisa Galea will discuss the neurological changes that occur during motherhood and their effect on behavior and brain health.
Dietary Spermidine Boosts Cognition in Insects and Rodents
Dietary Spermidine Boosts Cognition in Insects and Rodents
Ruth Williams | Apr 15, 2021
Mice and flies given the polyamine in their diet have increased brain cell metabolism and cognitive function, and epidemiological data hints at a similar benefit in humans.
Anesthesia Impairs Memory in Mice
Anesthesia Impairs Memory in Mice
Abby Olena | Apr 1, 2021
A study that compared several anesthetic regimens in rodents showed that only one—inhaled isoflurane—wasn’t detrimental to the activity of neurons in the hippocampus.
Immune Cell and Its Cytokine Control Exploratory Behavior in Mice
Immune Cell and Its Cytokine Control Exploratory Behavior in Mice
Ashley Yeager | Sep 14, 2020
Gamma delta T cells in the meninges of the brain release a cell signaling molecule that does more than protect mice from microbial pathogens.
Infographic: What Social Isolation Can Mean for the Brain
Infographic: What Social Isolation Can Mean for the Brain
Catherine Offord | Jul 13, 2020
People who show low social engagement over long periods of time often show reductions in cognitive function. Studies of the brain may provide clues about this correlation.
Adult-Born Neurons Strengthen Memories While Mice Sleep
Adult-Born Neurons Strengthen Memories While Mice Sleep
Ruth Williams | Jun 4, 2020
The activation of young brain cells in adult mice is necessary not just for forming memories, but consolidating them during rapid eye movement sleep, a study shows.
Unexpected Brain Strategy Links Two Events Separated by Time
Unexpected Brain Strategy Links Two Events Separated by Time
Alejandra Manjarrez | May 13, 2020
A new study in mice does not find evidence supporting two popular ideas for the mechanism for bridging the temporal time gap between two paired stimuli.
Image of the Day: A Mouse Brain Slice Becomes Art
Image of the Day: A Mouse Brain Slice Becomes Art
Amy Schleunes | Apr 1, 2020
A fluorescent image of murine hippocampal cells is the winning microscopy image from more than 400 submissions from 65 countries for Olympus’s 2019 Image of the Year Award.
Image of the Day: Synchronized Neurons
Image of the Day: Synchronized Neurons
Amy Schleunes | Feb 14, 2020
Memory formation in mice involves coordinated activity at the cellular level that likely leads to new circuits in the brain.
Image of the Day: Memory Erasure
Image of the Day: Memory Erasure
Amy Schleunes | Feb 12, 2020
By trimming synapses in the adult mouse hippocampus, microglia help facilitate forgetting.
Artificial Neurons Fire in Life-Like Patterns
Artificial Neurons Fire in Life-Like Patterns
Ashley Yeager | Dec 4, 2019
The silicon chips receive and send electrical signals, recreating activity from neurons in the rat brain that play a role in breathing and thinking.
Long-Lived Neural Stem Cells Identified in Living Mice
Long-Lived Neural Stem Cells Identified in Living Mice
Ashley Yeager | Oct 22, 2019
New, unpublished results show some of the cells produce new neurons for up to 90 days, much longer than a previously identified set of neural stem cells that only generate neurons for a month or two.
New Tools in the Works to Probe Adult Human Neurogenesis
New Tools in the Works to Probe Adult Human Neurogenesis
Ashley Yeager | Oct 7, 2019
Conflicting results on the existence of new neurons in adults have researchers designing new ways to identify and count neuronal progenitors—and finally get to the bottom of neurogenesis.
Nick Turk-Browne Explores the Neuroscience of Learning
Nick Turk-Browne Explores the Neuroscience of Learning
Catherine Offord | May 1, 2019
The Yale University cognitive neuroscientist studies how the brain extracts patterns from experiences.
More Evidence that Humans Do Appear to Create New Neurons in Old Age
More Evidence that Humans Do Appear to Create New Neurons in Old Age
Ashley Yeager | Mar 25, 2019
Despite doubts last year about human adult neurogenesis, a study shows even 80-year-olds develop new cells in the hippocampus, but such growth is diminished in patients with Alzheimer’s disease.
A New Role for Platelets: Boosting Neurogenesis After Exercise
A New Role for Platelets: Boosting Neurogenesis After Exercise
Katarina Zimmer | Mar 21, 2019
A mouse study finds that when blood platelets are activated during exercise, they release factors that increase the number of newborn neurons in the hippocampus.