First Mouse Embryos Made from Two FathersFirst Mouse Embryos Made from Two FathersFirst Mouse Embryos Made from Two Fathers
First Mouse Embryos Made from Two Fathers
The bipaternal pups died soon after birth, but mice with two mothers grew into fertile adults.
First Mouse Embryos Made from Two Fathers
First Mouse Embryos Made from Two Fathers

The bipaternal pups died soon after birth, but mice with two mothers grew into fertile adults.

The bipaternal pups died soon after birth, but mice with two mothers grew into fertile adults.

mouse study
Study Challenges CRISPR Method for Making Conditional Knockout Mice
Study Challenges CRISPR Method for Making Conditional Knockout Mice
Sukanya Charuchandra | Sep 28, 2018
Researchers from 17 labs report low efficacy rates for the popular technique.
New Technique Limits CRISPR-Cas9 Off-Target Mutations
New Technique Limits CRISPR-Cas9 Off-Target Mutations
Abby Olena | Sep 12, 2018
A mouse study details a method called VIVO that predicts the accuracy of any guide RNA.
Probiotics’ Effects on the Microbiome Vary Widely
Probiotics’ Effects on the Microbiome Vary Widely
Abby Olena | Sep 6, 2018
Experiments in mice and people find that probiotic supplements don’t consistently change the composition of the gut microbiome, and may have adverse effects after antibiotics.
Limited Meal Times Prevent Obesity in Mice Prone to Gaining Weight
Limited Meal Times Prevent Obesity in Mice Prone to Gaining Weight
Abby Olena | Aug 30, 2018
Even in mice with a busted circadian clock and an unhealthy diet, carefully timed feeding overcomes the rodents’ predispositions for metabolic diseases.
Long-Sought Hearing Channel Protein Found
Long-Sought Hearing Channel Protein Found
Abby Olena | Aug 22, 2018
After a decades-long pursuit, researchers have confirmed the identity of the pore of the mechanotransduction channel in vertebrates’ inner ear hair cells.
CRISPR Can Track Cellular History of a Mammalian Embryo
CRISPR Can Track Cellular History of a Mammalian Embryo
Sukanya Charuchandra | Aug 10, 2018
Researchers used the genome-editing technology to analyze the development of mouse tissues.
Laxative Causes Long-Term Changes to Mouse Microbiome
Laxative Causes Long-Term Changes to Mouse Microbiome
Abby Olena | Jun 14, 2018
Acute bouts of diarrhea could have lasting effects on the microbiota and host immune system activation, a mouse study suggests.
Ultrasound Fires Up the Auditory Cortex—Even Though Animals Can’t Hear It
Ultrasound Fires Up the Auditory Cortex—Even Though Animals Can’t Hear It
Abby Olena | May 24, 2018
Researchers have been using ultrasound to control brain activity, but studies in mice and guinea pigs show it also stimulates the auditory system, presenting a confounder for direct neural stimulation.
Reprogrammed Cells Treat Diabetes in Mice
Reprogrammed Cells Treat Diabetes in Mice
Abby Olena | May 2, 2018
Researchers used a trio of transcription factors to transform pancreatic duct cells in vivo into β-like cells that secrete insulin and improve diabetes symptoms.