Gut Microbes Help Coordinate Immune Activity in Mice
Gut Microbes Help Coordinate Immune Activity in Mice
The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.
Gut Microbes Help Coordinate Immune Activity in Mice
Gut Microbes Help Coordinate Immune Activity in Mice

The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.

The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.

mouse study
Cross-Resistance: One Cancer Therapy Can Undermine the Next
Cross-Resistance: One Cancer Therapy Can Undermine the Next
Sophie Fessl | Jul 16, 2021
Targeted cancer therapy may jeopardize the effectiveness of subsequent immunotherapy by reducing dendritic cell numbers and activation, according to study of mice and patient samples.
Infographic: Microbiome-Driven Adaptations in Animals
Infographic: Microbiome-Driven Adaptations in Animals
Catherine Offord | Jul 1, 2021
Researchers are using experiments and observational studies to look for host genetic variation that could be partly determined by the gut microbiota.
Mammals Can Use Their Intestines to Breathe
Mammals Can Use Their Intestines to Breathe
Abby Olena | May 14, 2021
Researchers show that both mice and pigs are capable of oxygenating their blood via the colon—a capacity that, if shared by humans, could be leveraged in the clinic to minimize the need for mechanical ventilation.
Brain’s Lymphatic System Tied to Alzheimer’s Symptoms in Mice
Brain’s Lymphatic System Tied to Alzheimer’s Symptoms in Mice
Amanda Heidt | May 4, 2021
A dysfunctional lymphatic system, described as a clogging of the brain’s sink, may explain why immunotherapies fail in some Alzheimer’s patients.
Human-Monkey Chimeras Shed Light on Development
Human-Monkey Chimeras Shed Light on Development
Abby Olena | Apr 15, 2021
Human stem cells injected into early monkey embryos proliferate and contribute to multiple cell lineages over 20 days of embryonic development.
High Stress Hormone Levels Halt Mouse Fur Growth
High Stress Hormone Levels Halt Mouse Fur Growth
Jef Akst | Apr 1, 2021
Corticosterone interferes with signaling in the skin that normally activates hair follicle stem cells, possibly explaining the link between stress and hair loss.
Anesthesia Impairs Memory in Mice
Anesthesia Impairs Memory in Mice
Abby Olena | Apr 1, 2021
A study that compared several anesthetic regimens in rodents showed that only one—inhaled isoflurane—wasn’t detrimental to the activity of neurons in the hippocampus.
Obesity-Linked Gut Bacteria May Worsen Graft-Versus-Host Disease
Obesity-Linked Gut Bacteria May Worsen Graft-Versus-Host Disease
Asher Jones | Apr 1, 2021
Altered gut microbiome composition in obese mice and human patients is linked with severity of disease after bone marrow transplantation, a study found.
Early Training Forestalls Motor, Memory Difficulties in Mouse Model of Rett Syndrome
Early Training Forestalls Motor, Memory Difficulties in Mouse Model of Rett Syndrome
Laura Dattaro | Mar 29, 2021
Manipulating the activity of neurons active during training had similar effects on the mice’s behavior.
Neurons for Taste Loosely Distributed in Mouse Gustatory Cortex
Neurons for Taste Loosely Distributed in Mouse Gustatory Cortex
Jef Akst | Mar 1, 2021
Neurological representations of different tastes—like those of different smells but unlike those of sight, hearing, and touch—do not cluster in distinct spots within a murine brain region, a study shows.
Organoids Repair Bile Ducts
Organoids Repair Bile Ducts
Abby Olena | Feb 18, 2021
Researchers determined that when introduced into damaged mouse or donated human livers, these lab-grown tissues could integrate into bile ducts and function normally.
Electric and Magnetic Field Treatments Lower Mouse Blood Sugar
Electric and Magnetic Field Treatments Lower Mouse Blood Sugar
Abby Olena | Oct 9, 2020
The effects seem to be mediated by a reactive oxygen species in the animals’ livers.
Cheese Preservative Slows Oral Cancer Spread in Mice: Study
Cheese Preservative Slows Oral Cancer Spread in Mice: Study
Max Kozlov | Oct 1, 2020
The results add to mounting evidence of microbes’ roles in tumor growth and point to the possibility of impeding malignancies by inhibiting bacteria.
Astrocytes, Not Just Neurons, Play a Role in Sleep
Astrocytes, Not Just Neurons, Play a Role in Sleep
Abby Olena | Sep 24, 2020
In mice, the brain’s main glial cell type exhibits distinctive patterns of activity across the sleep-wake cycle and influences the response to sleep deprivation.
How Mice Forget to Be Afraid
How Mice Forget to Be Afraid
Kerry Grens | May 1, 2020
The animals develop a new memory that overrides the fearful one by inhibiting the cells that encode the original memory.
Chemosensory Cells in the Nose Play a Role in Allergic Reactions
Chemosensory Cells in the Nose Play a Role in Allergic Reactions
Abby Olena | Jan 17, 2020
In mice, a group of nasal epithelial cells called brush cells release pro-inflammatory signals in response to allergens.
Alzheimer’s Drug Reduces Chagas Disease Infection in Mice
Alzheimer’s Drug Reduces Chagas Disease Infection in Mice
Emily Makowski | Dec 1, 2019
The drug, called memantine, could enter clinical trials to determine its effectiveness in humans.
Keto Diet Protects Mice from Flu
Keto Diet Protects Mice from Flu
Abby Olena | Nov 15, 2019
The low-carb, high-fat diet increases the presence of gamma-delta T cells in the animals’ lungs, improving a mucus barrier against the virus.
Image of the Day: Smartphone-Controlled Brains
Image of the Day: Smartphone-Controlled Brains
Nicoletta Lanese | Aug 7, 2019
A device implanted into mice can modulate brain circuit activity over long periods of time.