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Reprogrammed Cells Treat Diabetes in Mice
Abby Olena | May 2, 2018
Researchers used a trio of transcription factors to transform pancreatic duct cells in vivo into β-like cells that secrete insulin and improve diabetes symptoms.
Mouse Moms’ Behavior Affects Pups’ Genome Structures
Abby Olena | Mar 22, 2018
Mice who get less attention from their mothers have more copies of a common retrotransposon in the genomes of their hippocampal neurons.
Hungry Macrophages Keep Tattoos on Mice’s Skin
Diana Kwon | Mar 7, 2018
A new study reveals that a constant stream of ink-gobbling immune cells helps hold tattoos in place.
Maternal Response to Zika Damages Mouse Fetuses
Catherine Offord | Jan 5, 2018
Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.
Alcohol Damages Mouse DNA
Jef Akst | Jan 3, 2018
A byproduct of alcohol consumption causes mutations in the DNA of mouse blood stem cells, and some of the breaks are not repaired.
DNA-Delivered Antibodies Fight Off Lethal Bacterial Infection
Catherine Offord | Oct 3, 2017
Mice receiving the treatment produced their own monoclonal antibodies and survived infection with the life-threatening pathogen
How Immune Receptors Got into Mouse Noses
Shawna Williams | Sep 1, 2017
A study traces proteins’ evolution from the immune to the olfactory system.
A Bacterial Messenger Molecule Extends Healthspan
Sandhya Sekar | Aug 28, 2017
that make indoles protect older worms, flies, and mice from frailty.
Virtual Reality for Freely Moving Animals
Ashley Yeager | Aug 21, 2017
Experiments that place untethered fish, flies, and mice in simulated environments give clues about the animals’ social behavior.
First In Vivo Function Found for Animal Circular RNA
Catherine Offord | Aug 10, 2017
Mice lacking the RNA had deregulated microRNAs in the brain, disrupted synaptic communication, and behavioral abnormalities associated with neuropsychiatric disorders.