Menopause Caused by Men?

A new hypothesis holds that women become infertile later in life because males prefer younger mates.

Written byBob Grant
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

WIKIMEDIA, AZOREGWomen of a certain age undergo menopause not as an adaptation to allow older females to focus on helping out with rearing children—a prevailing notion known as the “grandmother theory”—but as an unintended consequence of males preferentially mating with younger females, according to a new study published in PLOS Computational Biology last week.

“How do you evolve infertility?” asked Rama Singh, the McMaster University biologist who led the study. “It is contrary to the whole notion of natural selection. Natural selection selects for fertility, for reproduction—not for stopping it.”

Singh and colleagues instead posit that menopause, a sudden drop in fertility that occurs in human females later in life, arose because competition for younger mates among men leaves older females with fewer chances to reproduce. As that selective force, which protects fertility in younger women, slackens, the genetic mutations that bring on menopause are allowed to accumulate, causing infertility. “This theory says that natural selection doesn’t have to do anything,” Singh said in a statement. “If women were reproducing all along, and there were no preference against older ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

    View Full Profile
Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies