Skip to main content

More Small Biotech Firms Are `Living On The Edge'

Directory assistance for the 919 area code in North Carolina no longer lists a phone number for Macronex Inc., a small biotechnology company located in Morrisville. Although technically still a going concern, Macronex currently has only two employees and is in the process of going out of business. STRAPPED: ImmunoGen CEO Mitchel Sayare observes, from hard experience, that "things are not going well for companies that don't have enough cash." "We've pretty much closed our operation . . . a cas

Written byLee Katterman
| 9 min read

Register for free to listen to this article
Listen with Speechify
0:00
9:00

ImmunoGen CEO STRAPPED: ImmunoGen CEO Mitchel Sayare observes, from hard experience, that "things are not going well for companies that don't have enough cash."

The pressure is on for many biotechnology companies, from very small ones such as Macronex to those with up to a few hundred employees that nonetheless lack a product to sell. For the last several years, financing has become more and more difficult to find.

Some, like Macronex, have closed down. Other firms have streamlined, hoping to conserve their precious remaining cash until a "focused" R&D program yields the kind of results that will attract investors again. Any "surprises" during clinical testing, and a firm may be forced to go under.

A merger of two small biotechs is also a possibility, especially if one company has cash and no products anywhere near ready for the market and the other has late-stage R&D under way but little money to ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

Related Topics

Published In

Related articles background image
August 2026 Digest cover
August 2026

Epic Fail: Sea-Monkeys Sabotage Fieldwork

When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.

View this Issue
Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Miltenyi
Overcoming Immunotherapy Resistance in Liver Cancer

Overcoming Immunotherapy Resistance in Liver Cancer

Axion Biosystems
Optimizing NGS Library Preparation for Reliable Sequencing Data

Optimizing NGS Library Preparation for Reliable Sequencing Data

Covaris
Using TCR Repertoire Sequencing to Advance Immunology Research

Using TCR Repertoire Sequencing to Advance Immunology Research

Miltenyi

Products

Sino Biological Logo

Sino Biological Launches SuperNuclease ® Pro with Free Trial Program

Sino Biological Logo

Sino Biological Launches Precisely Characterized Full-Length p-Tau217 Protein to Advance Next-Generation Alzheimer’s Biomarker Assay Development

A photo of a scientist placing the Resipher device on a 96-well plate.

Resipher: Continuous Live-Cell Mitochondrial Respiration Monitoring in 96-Well Plates

Lucid Scientific logo
Conceptual image of ice and frost.

The VAULT100 PRO: Inside the most advanced Stirling Ultracold ULT freezer ever built.

Stirling Ultracold logo