More Small Biotech Firms Are `Living On The Edge'

Directory assistance for the 919 area code in North Carolina no longer lists a phone number for Macronex Inc., a small biotechnology company located in Morrisville. Although technically still a going concern, Macronex currently has only two employees and is in the process of going out of business. STRAPPED: ImmunoGen CEO Mitchel Sayare observes, from hard experience, that "things are not going well for companies that don't have enough cash." "We've pretty much closed our operation . . . a cas

| 9 min read

Register for free to listen to this article
Listen with Speechify
0:00
9:00
Share

ImmunoGen CEO STRAPPED: ImmunoGen CEO Mitchel Sayare observes, from hard experience, that "things are not going well for companies that don't have enough cash."

The pressure is on for many biotechnology companies, from very small ones such as Macronex to those with up to a few hundred employees that nonetheless lack a product to sell. For the last several years, financing has become more and more difficult to find.

Some, like Macronex, have closed down. Other firms have streamlined, hoping to conserve their precious remaining cash until a "focused" R&D program yields the kind of results that will attract investors again. Any "surprises" during clinical testing, and a firm may be forced to go under.

A merger of two small biotechs is also a possibility, especially if one company has cash and no products anywhere near ready for the market and the other has late-stage R&D under way but little money to ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • Lee Katterman

    This person does not yet have a bio.

Published In

Share
Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

View this Issue
Faster Fluid Measurements for Formulation Development

Meet Honeybun and Breeze Through Viscometry in Formulation Development

Unchained Labs
Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

sartorius logo
An illustration of PFAS bubbles in front of a blue sky with clouds.

PFAS: The Forever Chemicals

sartorius logo
Unlocking the Unattainable in Gene Construction

Unlocking the Unattainable in Gene Construction

dna-script-primarylogo-digital

Products

Metrion Biosciences Logo

Metrion Biosciences launches NaV1.9 high-throughput screening assay to strengthen screening portfolio and advance research on new medicines for pain

Biotium Logo

Biotium Unveils New Assay Kit with Exceptional RNase Detection Sensitivity

Atelerix

Atelerix signs exclusive agreement with MineBio to establish distribution channel for non-cryogenic cell preservation solutions in China

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

Thermo Fisher Logo