Mutated Gene Could Raise Marine Mammals’ Vulnerability to Pesticides

The resulting lost protein, PON1, breaks down organophosphates in land mammals.

Written byShawna Williams
| 1 min read
two manatees at the ocean floor

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ABOVE: ROBERT K. BONDE, USGS - GAINESVILLE

Organophosphates, a class of chemicals that includes weapons such as sarin and agricultural pesticides, could pose a unique risk to marine mammals, according to a study in the August 10 issue of Science. Ocean-dwelling animals that trace their ancestry to various land mammals independently acquired mutations in the gene PON1 that render it useless in breaking down the chemicals, researchers found.

“Marine mammals may be at a great disadvantage in the Anthropocene if run-off of this agricultural product [organophosphates] into the marine environment continues,” the study authors write in their paper.

The researchers came upon PON1 while looking for common genetic changes associated with the transition from land to sea. Such an evolution has occurred at least three times, giving rise to today’s whales and dolphins; manatees and dugongs; and walruses and sea lions. Among other adaptations among all the marine mammals, a ...

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Meet the Author

  • Shawna was an editor at The Scientist from 2017 through 2022. She holds a bachelor’s degree in biochemistry from Colorado College and a graduate certificate in science communication from the University of California, Santa Cruz. Previously, she worked as a freelance editor and writer, and in the communications offices of several academic research institutions. As news director, Shawna assigned and edited news, opinion, and in-depth feature articles for the website on all aspects of the life sciences. She is based in central Washington State, and is a member of the Northwest Science Writers Association and the National Association of Science Writers.

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