Tracers injected in the controlateral side of the mouse cortex highlight fluorescently labeled axons (green) and neurons (pink).CELL, ZINGG ET AL.
Although US and EU leadership have recently pledged millions of dollars to support the development of a comprehensive understanding of the neuronal connections throughout the brain, researchers have been toiling away at this goal for years. Most recently, a group from the University of Southern California (USC) has published a carefully constructed “connectome,” built from the analysis of hundreds of neuronal pathways in the mouse cortex. The work appeared today (February 27) in Cell.
“The one thing I really appreciate about this work is that it combines the large data scale with careful, manual annotation and analysis of the data,” said Pavel Osten, a neuroscientist at Cold Spring Harbor Laboratory (CSHL) in New York, who was ...