New Disrupters Help Cell Biologists Retrieve Products

Many experiments in cell biology require researchers to break open cells and then retrieve their contents. For example, the production of recombinant proteins in biotechnology relies on cell and tissue cultures--and cell disruption is essential to retrieving sought-after cell products. The technology used must be powerful enough to disrupt cell membranes and, possibly, cell walls, yet gentle enough so that the organelles and macromolecules inside the cells are not smashed, shattered, or boiled

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scale cell-disruption technologies. BioSpec Products Inc. P.O. Box 722 Bartlesville, Okla. 74005 Phone/Fax: (918) 336-3363 Products: Mini Beadbeater, $988; Biohomogenizer (rotor-stator), $485 Cole-Parmer Instrument Co. 7425 North Oak Park Ave. Chicago, Ill. 60648 (708) 647-7600 Fax: (708) 647-9660 Products: 50-watt ultrasonic processor, $1,495; shaking bead mill, $485-530; rotor-stator generators, $500-$690 Glas-Col Apparatus Co. 711 Hulman St. Terre Haute, Ind. 47802 (812) 235-6167 Fax: (812) 234-6975 Product: BioNeb Cell Disruption System, $3,965-$4,065, depending on capacity Microfluidics 30 Ossipee Rd. P.O. Box 9101 Newton, Mass. 02164-9101 (800) 370-5452 Fax: (617) 965-1213 Product: Cell Disruption Microfluidizer, $21,690 Omni International Inc. 6530 Commerce Court Suite 200 E Gainesville, Va. 22065 (800) 776-4431 Fax: (703) 347-5352 Products: Mixer Homogenizer, $2,400, Micro Homogenizer, $1,100 Parr Instrument Co. 211 53rd St. Moline, Ill. 61265-9984 (309) 762-7716 Fax: (309) 762-9453 Product: Cell Disruption Bomb, $1,120-$7,700, depending on capacity Sonics and Materials Inc. Kenosia Avenue Danbury, Conn. 06810 (203) ...

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