New England Biolabs® Introduces NEBNext® Custom RNA Depletion Design Tool and RNA Depletion Core Reagent Set for Customizable RNA Depletion

Combination of free user-friendly web tool, to obtain custom probe sequences, and enzyme-based technology allows for efficient depletion of abundant RNAs for virtually any organism and sample type.

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New England Biolabs (NEB®) announced further expansion of its RNA depletion product portfolio with the launch of the NEBNext Custom RNA Depletion Design Tool and NEBNext RNA Depletion Core Reagent Set. Together, these enable a fully customizable workflow for improved removal of specific RNAs, including abundant RNAs such as ribosomal RNA (rRNA). This approach can be applied to any sample, including those from less commonly used organisms, and from difficult sample types such as formalin-fixed paraffin embedded (FFPE) tissue samples.

"The removal of abundant RNA is a critical step for many RNA-based applications, including RNA sequencing" said Fiona Stewart, Ph.D., Product Portfolio Manager, Next Generation Sequencing at NEB. "However, removing undesirable RNA sequences from atypical samples, which are not compatible with existing RNA depletion kits on the market, is a challenge faced by many researchers. This problem led us to develop a fully customizable and user-friendly solution that allows scientists ...

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