An advert for Diovan in a Hong Kong trainWIKIMEDIA, MK2010Novartis may have supported the work of researchers whose favorable studies of one of the company’s best-selling drugs have been retracted, according to a Japanese newspaper. Novartis has distanced itself from the researchers, but the newspaper reported this week that the company had already invested $1 million in their work, a Nature blog reported.
The blood-pressure drug valsartan (Diovan) was the best-selling drug for Novartis’s Japanese subsidiary in 2011, netting $1.3 billion dollars. That boom followed the publication of studies from Hiroaki Matsubara’s group at the Kyoto Prefectural University of Medicine (KPUM) suggesting that valsartin can also reduce the risk of stroke and heart attack—results that made their way into advertisements for the drug, according to Nature.
But in December 2012, two of Matsubara’s papers on Diovan were retracted by the Japanese Circulation Society for “serious errors in data analysis.” Matsubara denied any deliberate wrongdoing and stood by his results, and a university investigation revealed no misconduct. But in February this year, the European Society of Cardiologists retracted another of Matsubara’s Diovan papers, citing “critical problems” with some of ...
