The next generation OmniPAGE VS20WAVE-DGGE from Cleaver Scientific is a flexible Denaturing Gradient Gel Electrophoresis (DGGE) system. Modular in design the system can be simply adapted to perform most single-base pair mutation detection techniques that are used in DNA mutation analysis.
Denaturing gradient gel electrophoresis (DGGE) is a molecular fingerprinting method that separates polymerase chain reaction generated DNA products. The polymerase chain reaction (PCR) of environmental DNA can generate templates of differing DNA sequence that represent many of the dominant microbial organisms. However, since PCR products from a given reaction are of similar size (bp), conventional separation by agarose gel electrophoresis results only in a single DNA band that is largely non-descriptive. DGGE can overcome this limitation by separating PCR products based on sequence differences that results in differential denaturing characteristics of the DNA.
Incorporating proprietary vertical screw-clamp technology, the VS20WAVE-DGGE is fully equipped with temperature control unit, stirrer, and ...
