Organs on Demand

3-D printing has made inroads in the clinic, but constructing functional complex organs still faces major hurdles.

Written byKate Yandell
| 13 min read

Register for free to listen to this article
Listen with Speechify
0:00
13:00
Share

RENAL RECONSTRUCTION: Wake Forest postdoctoral fellow Hyun-Wook Kang operates a 3-D printer that is making a kidney prototype with cells and biomaterials.IMAGE COURTESY OF WAKE FOREST INSTITUTE FOR REGENERATIVE MEDICINE

On a stage in front of an audience of thousands, a futuristic-looking machine squirted gel from a nozzle. Layer by layer, it built up the material, shaping it into a curved, pink, kidney-shape structure based on a medical CT scan of a real organ.

It was 2011, and Anthony Atala, director of the Wake Forest Institute for Regenerative Medicine, was demonstrating his progress in using three-dimensional (3-D) printing to make a kidney during his TED Talk. Like a TV chef pulling a previously baked casserole from the oven, Atala soon held a bean-shape object in his gloved hands. “Here it is,” he said. “You can actually see the kidney as it was printed earlier today.” The audience erupted into cheers.

But Atala had not made ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies