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Fixing the Problem with Induced Pluripotent Stem Cells

Tanvir Khan, PhD | Oct 31, 2023 | 4 min read

A new strategy prevents reprogramming-induced epigenetic aberrations in human induced pluripotent stem cells.

A clinician holding a graphic of the lungs on a tablet

Stem Cells Breathe New Life into Lungs

Aparna Nathan, PhD | Oct 30, 2023 | 3 min read

New studies proposed using stem cells to make long-lasting lung grafts.

Modeling Human Disease and Development with Organoids

The Scientist’s Creative Services Team | 1 min read

Discover how scientists use cardiac and skin organoids to study differentiation and toxicity.

Fresh asparagus sliced horizontally, revealing inner microchannel structure.

Food for Thought: A Recipe for Regenerating Nerves

Iris Kulbatski, PhD | Oct 23, 2023 | 3 min read

Al dente asparagus stalks may hold the key to successful neural stem cell therapy for repairing injured axons.

A graphic of the female reproductive system

Differentiated Stem Cells Can Kickstart Fertility in Mice

Aparna Nathan, PhD | Oct 23, 2023 | 3 min read

Ovarian cells derived from stem cells restore hormones and cells needed to produce pups.

Best Practices for Organoid Technologies

The Scientist’s Creative Services Team | 1 min read

Dosh Whye will discuss best practices for organoid modeling and how researchers leverage the latest technologies to achieve their goals.

This is an image of a bioluminescent from gene expression reporter in stem cells from a rhinoceros.

A Stem Cell Zoo Reveals Surprising Differences in Embryogenesis

Ida Emilie Steinmark, PhD | Sep 1, 2023 | 2 min read

By comparing stem cells from six mammals of different sizes, scientists discovered stark differences in embryonic development paces.

On the left is a normally developing mouse embryo, on the right is a slightly larger mouse embryo that also contains horse cells that glow green.

Chimera research opens new doors to understanding and treating disease

Hannah Thomasy, PhD, Drug Discovery News | Aug 9, 2023 | 10 min read

Animals with human cells could provide donor organs or help us understand neuropsychiatric disorders.

Key Strategies for Better Stem Cell Workflows

Solutions for Optimizing Stem Cell Therapy Development

Sartorius | 1 min read

Discover how process knowledge is integral to stem cell workflow improvement and optimization.

Islands of Knowledge: Hairy Skin Moles Make Their Mark

Iris Kulbatski, PhD | Aug 7, 2023 | 3 min read

Skin moles that sprout thick, long hairs produce signaling molecules that stimulate hair follicle stem cells to initiate new hair growth. This discovery may make baldness a thing of the past.

Medical illustration of brain cancer with a microscopic magnification of malignant cells dividing in the tumor microenvironment.

Capturing the Brain Tumor Microenvironment with Tissue Engineering

Deanna MacNeil, PhD | Aug 4, 2023 | 3 min read

Researchers built a 3D glioblastoma model to study therapeutic resistance and improve drug screening systems.

Discover how counterflow centrifugation streamlines cell therapy workflows

Closed Cell Processing Systems for Cell Therapy Workflows

Thermo Fisher Scientific | 1 min read

Closed systems increase cell therapy manufacturing process efficiency.

Photo of Rosa Bacchetta, associate professor of pediatrics at Stanford University

The Future of Gene Therapy for a Rare Pediatric Autoimmune Disease

Niki Spahich, PhD | Jul 10, 2023 | 3 min read

By editing a mutated immune regulatory gene in patient cells, Rosa Bacchetta brings hope to those suffering from IPEX syndrome.

Neurons (green) fire differently depending on whether the astrocytes (red) they are grown with are cultivated from people with or without fragile X.

Astrocytes Fuel Erratic Firing in Fragile X Neurons

Lauren Schenkman, Spectrum | May 30, 2023 | 4 min read

This new understanding could one day lead to targeted treatments.

Learn how excessive oxygen availability during cell culture causes abnormal cell behavior

What Oxygen Level Is Biologically Relevant For Cell Culture?

Thermo Fisher Scientific | 1 min read

Normoxic atmospheric conditions provide excessive oxygen availability, leading to abnormal cell behavior.

Bladder epithelial tissue, where cell junctions are shown in green and nuclei in blue. This was grown in vitro from cells taken from mice with chronic cystitis.

Bladder ‘Memory’ Influences Urinary Tract Infection Recurrence in Mice

Alejandra Manjarrez, PhD | Apr 12, 2023 | 3 min read

Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.