Privatizing the Human Genome?

Principals behind joint-venture proposal and public effort seek to define relationships A private effort to sequence the human genome four years ahead of the Human Genome Project's 2005 goal could either compete directly with the federal project or meld seamlessly with it. Before any relationship between the two efforts becomes formalized, scientists and federal officials involved with the Human Genome Project must determine whether the private approach will work, who will own the data, how qu

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The private effort, a joint venture between Perkin-Elmer Inc., a Norwalk, Conn., manufacturer of sequencing equipment, and J. Craig Venter , president and director of The Institute for Genomic Research (TIGR) in Rockville, Md., would be embodied by a new company formed to sequence the entire human genome by 2001, and at an estimated cost of $150 million to $300 million. Faster, more automated sequencing machines recently unveiled by Perkin-Elmer, and a different sequencing strategy espoused by Venter make that target feasible. The federally sponsored Human Genome Project, which has a total estimated budget of $3 billion, is on schedule to finish sequencing the approximately 3 billion base pairs of DNA that make up the human genome by 2005.

MIXED SIGNALS: NHGRI's Francis Collins has sent mixed signals about whether the public and private sequencing ventures can cooperate. Francis Collins , director of the National Human Genome Research Institute, cautions ...

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