Research Notes

Common Denominator in Breast Cancer While breast cancer devastates all those affected, researchers have had a tough time finding a common denominator at the molecular level. Now Saraswati Sukumar, associate professor of oncology and pathology, and colleagues at the Johns Hopkins Oncology Center have identified a molecular alteration affecting the vast majority of primary breast cancers. Hypermethylation of the 14-3-3 s gene (s) and subsequent loss of expression are the most consistent molecular