Research Products for Wnt Signaling Pathway Investigations

Anglo-American life science firm AMSBIO offers a comprehensive selection of products for Wnt signaling research including recombinant proteins, stable reporter cell lines, polyclonal antibodies and ELISA assay kits. Wnt proteins are a family of cysteine-rich secreted polypeptides involved in important cell functions including cell to cell communication, cell proliferation, cell migration, cell polarity, survival and self-renewal. In particular Wnt3a signals play an important role in the ability of organoids to expand. Additionally, loss of activation of Wnt expression has been associated with alteration of cell fate, morphogenesis and mitogenesis which has considerable relevance in developmental biology and oncology research. AMSBIO has introduced a new range of Wnt human and mouse recombinant proteins available in both high (85 - 90%) and lower (75%) purities. Suitable for various cell based assays and treatments, the human recombinant proteins are purified from HEK293 cells while the mouse proteins are expressed in CHO cells. In ...