Science Cracks a Superhero’s Powers

A spoof research paper elucidates the molecular keys to Wolverine’s regenerative abilities.

Written byBob Grant
| 1 min read

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Wolverine presumably retracted his adamantium-laced bone claws while participating in the research.FLICKR, JD HANCOCKX-Man and serial regenerator Wolverine is able to rapidly heal wounds received in the fight for justice and mutant equality thanks to a protein called Howlett, which shares many characteristics of the Amblox protein in the axolotl, an amphibian that can regenerate whole limbs. This according to a spoof research paper published earlier this year in the Journal of Superhero Mutational Science and penned by Canadian researchers along with fellow mutants Cyclops and Charles Xavier.

University of British Columbia grad students Sigrid Alvarez and Emma Conway authored the manuscript in collaboration with UBC biochemist Leonard Foster and submitted it for publication in the 8th issue of UBC’s The Science Creative Quarterly.

The researchers knocked down howlett, the gene that codes for Wolverine’s regeneration protein, performing parallel experiments with the amblox gene in axolotls. They found that both in the superhero and in the amphibian, blocking the translation of Howlett and Amblox severely reduced the organisms’ healing abilities. The findings and future research into the signaling pathways and regulatory mechanisms involved in regeneration in Wolverine and axolotls may inform the field of regenerative medicine.

(Hat tip to Boing Boing.)

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Meet the Author

  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

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