Science Cracks a Superhero’s Powers

A spoof research paper elucidates the molecular keys to Wolverine’s regenerative abilities.

Written byBob Grant
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

Wolverine presumably retracted his adamantium-laced bone claws while participating in the research.FLICKR, JD HANCOCKX-Man and serial regenerator Wolverine is able to rapidly heal wounds received in the fight for justice and mutant equality thanks to a protein called Howlett, which shares many characteristics of the Amblox protein in the axolotl, an amphibian that can regenerate whole limbs. This according to a spoof research paper published earlier this year in the Journal of Superhero Mutational Science and penned by Canadian researchers along with fellow mutants Cyclops and Charles Xavier.

University of British Columbia grad students Sigrid Alvarez and Emma Conway authored the manuscript in collaboration with UBC biochemist Leonard Foster and submitted it for publication in the 8th issue of UBC’s The Science Creative Quarterly.

The researchers knocked down howlett, the gene that codes for Wolverine’s regeneration protein, performing parallel experiments with the amblox gene in axolotls. They found that both in the superhero and in the amphibian, blocking the translation of Howlett and Amblox severely reduced the organisms’ healing abilities. The findings and future research into the signaling pathways and regulatory mechanisms involved in regeneration in Wolverine and axolotls may inform the field of regenerative medicine.

(Hat tip to Boing Boing.)

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Related Topics

Meet the Author

  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

    View Full Profile
Share
Image of a man in a laboratory looking frustrated with his failed experiment.
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Graphic of amino acid chains folded into proteins

Expi293™ PRO Expression System: Higher Yields Across a Wider Variety of Proteins

Thermo Fisher Logo