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A brittle star with its thin, serpent-like arms against a black background.
Diving Into the Brittle Star Genome to Understand the Evolution of Regeneration
The sequenced genome of the brittle star revealed unique gene arrangements and provides insights into ancient genes involved in limb regeneration.
Diving Into the Brittle Star Genome to Understand the Evolution of Regeneration
Diving Into the Brittle Star Genome to Understand the Evolution of Regeneration

The sequenced genome of the brittle star revealed unique gene arrangements and provides insights into ancient genes involved in limb regeneration.

The sequenced genome of the brittle star revealed unique gene arrangements and provides insights into ancient genes involved in limb regeneration.

regeneration

An African killifish 
How Cells Know Where to Grow After Injury
Deanna MacNeil, PhD | Oct 16, 2024 | 3 min read
Fish fins and single-cell sequencing help scientists glean new insights into tissue regeneration.
Red and gray round cells floating on a red background. 
Low Intracellular Iron Levels May Keep Blood Stem Cells Young
Alejandra Manjarrez, PhD | Apr 8, 2024 | 3 min read
Removing excess iron from aging mouse blood-forming cells enhances their regenerative capacity.
Modeling Human Disease and Development with Organoids
Modeling Human Disease and Development with Organoids
The Scientist | 1 min read
Discover how scientists use cardiac and skin organoids to study differentiation and toxicity. 
Tadpole
How Tadpoles Garner the Energy to Regenerate Their Tails
Natalia Mesa, PhD | Mar 1, 2023 | 3 min read
A metabolic pathway used for tail regrowth may be critical for tissue regeneration in some cells, a study suggests. 
Infographic showing the process of tail regeneration in tadpoles
Infographic: How Tadpoles Use Glucose to Fuel Tail Regrowth
Natalia Mesa, PhD | Mar 1, 2023 | 1 min read
Unlike other fast-growing cells, regenerating tadpole cells fuel growth using the pentose phosphate pathway rather than glycolysis, a study indicates.
Technique Talk: Supporting Organoid Growth in 3D Cell Culture
The Scientist Creative Services Team in collaboration with Bio-Techne | 1 min read
In this workshop, you will learn how to optimally culture organoids and support their growth after genetic manipulation.
A nine-banded armadillo walking on dry grass.
Leprosy Bacterium Rejuvenates Armadillos’ Livers
Alejandra Manjarrez, PhD | Nov 15, 2022 | 4 min read
Mycobacterium leprae appeared to reprogram the animals’ livers to a state partially resembling early development, resulting in healthy organ growth.
Micrograph of kidney tissue from a mouse
Vesicles from Young Mice Alleviate Signs of Aging in Older Animals
Catherine Offord | Oct 19, 2022 | 4 min read
Mice that received the stem cell–derived treatment were less frail compared with controls, a study reports.
Improving Cardiac Cell Therapy Persistence
The Scientist Speaks Ep. 13 - The Long Haul: Improving Cardiac Cell Therapy Persistence
Niki Spahich, PhD | 1 min read
Researchers remuscularize the heart after cardiac infarction with stem cell-derived cardiomyocytes and ready-made microvessels.
Thomas Lozito poses with Donald, one of his mourning geckos.
Thomas Lozito Is Figuring Out How Lizards Rebuild
Connor Lynch | Feb 14, 2022 | 4 min read
The University of Southern California bioengineer studies how lizards regrow their tails, with the goal of one day inducing regeneration in humans.
Stem Cells in Human Teeth Follow the Rules of Their Environment
Roni Dengler, PhD | Feb 7, 2022 | 2 min read
How stem cells in human teeth respond to different environmental conditions offers clues for regenerative medicine.
Technique Talk: 2D Stem Cell Culture
The Scientist | 1 min read
In this workshop, you will learn tips and tricks for culturing stem cells in 2D.
A frog partially submerged in water looking straight ahead
Drug Cocktail Triggers Regeneration of Amputated Frog Legs
Dan Robitzski | Jan 26, 2022 | 3 min read
A new chemical treatment allowed African clawed frogs, which normally don’t regenerate limbs, to regrow functional hind legs following amputation.
A semi-translucent hydra, complete with a body column, head, and multiple tentacles, is pictured in front of a gray background.
How Hydras Regenerate Decapitated Heads
Dan Robitzski | Dec 14, 2021 | 5 min read
Hydra vulgaris constantly replenish the cells in their heads and grow new ones to reproduce asexually. But gene expression analyses reveal that regenerating a head after an injury is a very different process.
The MSC: Regeneration Orchestrator
The Scientist Staff | 7 min read
Scientists uncover the promise of mesenchymal stem cells (MSCs), also known as medicinal signaling cells, to modulate the immune system and regenerate tissue.
Lizard on glass tank
Engineered Stem Cells Grant Geckos “Perfectly” Regenerated Tails
Chloe Tenn | Nov 5, 2021 | 4 min read
Geckos injected with neural stem cells modified to block cartilage growth developed the skeletal and nervous components normally lacking from regrown tails.
a spiny mouse sits on a piece of wood holding a small morsel to its mouth
Spiny Mice Appear to Regenerate Damaged Kidneys
Dan Robitzski | Nov 3, 2021 | 5 min read
The mice, already known to regenerate skin, seem to avoid the tissue scarring that leads to organ failure in other animals.
An underwater photo of the solitary tunicate Polycarpa mytiligera growing on a coral in the Red Sea
When Severed, This Solitary Tunicate Regrows as Three New Animals
Amanda Heidt | May 13, 2021 | 4 min read
While regeneration has long been the domain of colonial tunicates, a solitary species of sea squirt was able to regenerate into multiple, fully functional individuals within a month of being cut up.
Infographic: Anatomical Construction by Cell Collectives
Michael Levin | Sep 1, 2020 | 3 min read
Understanding this complex and still largely enigmatic process will pave the way for researchers to control the development of new morphologies.
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