Scientists Confirm Zika's Link to Neurological Disorders

A literature review of more than 100 studies confirms that microcephaly, Guillain-Barre syndrome, and related conditions are linked to Zika virus infection.

Written byDiana Kwon
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

PIXABAY, ARTSYBEEThere is now sufficient evidence to conclude that the mosquito-borne Zika virus causes brain-related birth defects such as microcephaly, and triggers Guillain-Barre Syndrome (GBS), according to a January 3 literature review published in PLOS Medicine.

Last March, the World Health Organization announced that there was strong agreement among scientists that Zika caused neurological disorders such as microcephaly. To evaluate the strength of this evidence, a group of WHO researchers, led by Fabienne Krauer at the University of Bern in Switzerland, conducted a review of 72 studies that investigated the link between Zika and congenital brain abnormalities and 36 studies that looked at Zika’s link with GBS. Krauer and colleagues confirmed that more than half of these studies met most of the criteria for causality. An independent panel of experts confirmed that these 108 studies constitute sufficient evidence that Zika infection can cause congenital brain defects and trigger GBS.

But some limitations remain. For instance, the researchers point out that studies ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • Diana is a freelance science journalist who covers the life sciences, health, and academic life. She’s a regular contributor to The Scientist and her work has appeared in several other publications, including Scientific American, Knowable, and Quanta. Diana was a former intern at The Scientist and she holds a master’s degree in neuroscience from McGill University. She’s currently based in Berlin, Germany.

    View Full Profile
Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies