New Screening Approach Reveals Novel Regulators of Microcephaly
New Screening Approach Reveals Novel Regulators of Microcephaly
Researchers combine organoids, CRISPR-Cas9, and cellular barcoding technologies to identify genes that influence brain size.
New Screening Approach Reveals Novel Regulators of Microcephaly
New Screening Approach Reveals Novel Regulators of Microcephaly

Researchers combine organoids, CRISPR-Cas9, and cellular barcoding technologies to identify genes that influence brain size.

Researchers combine organoids, CRISPR-Cas9, and cellular barcoding technologies to identify genes that influence brain size.

microcephaly
Does Prior Dengue Exposure Help or Hurt a Zika Infection?
Does Prior Dengue Exposure Help or Hurt a Zika Infection?
Diana Kwon | Mar 6, 2019
Animal and cell culture studies show evidence that dengue antibodies can both neutralize and enhance Zika, but human investigations have only found protective effects.
Viruses Related to Zika May Also Harm Fetuses
Viruses Related to Zika May Also Harm Fetuses
Ruth Williams | Jan 31, 2018
Studies in mice suggest that other flaviviruses, such as West Nile virus and Powassan virus, may cause birth defects, too. 
Parts of U.S. Saw an Increase in Zika-Linked Birth Defects in 2016
Parts of U.S. Saw an Increase in Zika-Linked Birth Defects in 2016
Katarina Zimmer | Jan 26, 2018
The rise occurred in areas with confirmed local transmission, according to a new CDC report. 
Maternal Response to Zika Damages Mouse Fetuses
Maternal Response to Zika Damages Mouse Fetuses
Catherine Offord | Jan 5, 2018
Signaling pathways triggered by the mother’s immune system may cause complications during fetal development.
A Single Mutation in Zika Led to Devastating Effects
A Single Mutation in Zika Led to Devastating Effects
Anna Azvolinsky | Sep 28, 2017
One amino acid change within a viral structural protein makes the difference between mild cases of brain damage and severe microcephaly in mice.
Zika Virus Persists in the Nervous System and Elsewhere
Zika Virus Persists in the Nervous System and Elsewhere
Ruth Williams | Apr 27, 2017
Studies of infected rhesus monkeys reveal the virus’s long-term hiding places in the body.
CDC Recommends Brain Imaging for Zika-Affected Babies
CDC Recommends Brain Imaging for Zika-Affected Babies
Tracy Vence | Apr 6, 2017
Infants born to mothers who were infected with the virus during pregnancy—including babies who do not show signs of microcephaly—may experience other birth defects.
Scientists Confirm Zika's Link to Neurological Disorders
Scientists Confirm Zika's Link to Neurological Disorders
Diana Kwon | Jan 3, 2017
A literature review of more than 100 studies confirms that microcephaly, Guillain-Barre syndrome, and related conditions are linked to Zika virus infection.
Zika’s Persistence in Infants
Zika’s Persistence in Infants
Ben Andrew Henry | Dec 14, 2016
Microcephaly is but one of the birth defects associated with infection in babies, a study suggests. The virus persists and replicates in the infant brain, according to another study.
Zika-Associated Microcephaly Can Present After Birth
Zika-Associated Microcephaly Can Present After Birth
Tracy Vence | Nov 22, 2016
Researchers report on more than a dozen cases in which babies who showed signs of in-utero infection but were born without symptoms of congenital Zika syndrome went on to develop brain abnormalities. 
Zika Infects Adult Monkeys’ Brains
Zika Infects Adult Monkeys’ Brains
Kerry Grens | Oct 5, 2016
A laboratory study finds the virus in the cerebellum in addition to body fluids.
Study: Zika-Exposed Babies 50 Times More Likely to Be Born with Microcephaly
Study: Zika-Exposed Babies 50 Times More Likely to Be Born with Microcephaly
Jef Akst | Sep 16, 2016
Scientists estimate the risk to fetuses exposed to the virus in utero.
Zika Update
Zika Update
Tanya Lewis | Jul 26, 2016
Researchers in Brazil ponder whether virus alone causes birth defects; Colombia declares epidemic over; first Zika-related microcephaly case reported in Europe
Zika Update
Zika Update
Tanya Lewis | Jul 5, 2016
Sexual transmission more common than thought; NIH to track infections among Olympians; Zika-related birth defects draw attention to another common virus
Improving Zika Virus Detection in Infants
Improving Zika Virus Detection in Infants
Catherine Offord | Jun 29, 2016
Head circumference is not an accurate indicator of viral infection in newborns, researchers report.
Study: No Zika–Microcephaly Link Late in Pregnancy
Study: No Zika–Microcephaly Link Late in Pregnancy
Catherine Offord | Jun 16, 2016
Babies born to mothers infected with Zika during the third trimester have a low risk of developing microcephaly, researchers report.
WHO to People in Zika-Affected Areas: Consider Delaying Pregnancy
WHO to People in Zika-Affected Areas: Consider Delaying Pregnancy
Tanya Lewis | Jun 10, 2016
New recommendation from the World Health Organization could affect millions of people across Latin America and the Caribbean.
Potential Route for Zika from Mother to Fetus
Potential Route for Zika from Mother to Fetus
Catherine Offord | May 31, 2016
Placental macrophages called Hofbauer cells are particularly vulnerable to infection by the virus, a study shows.
Scientists Estimate Zika-Related Microcephaly Risk
Scientists Estimate Zika-Related Microcephaly Risk
Catherine Offord | May 25, 2016
A fetus whose mother is infected with Zika during the first trimester of her pregnancy has a risk of between 1 percent and 13 percent of developing microcephaly, according to a study.