Signal Transduction

Edited by: Thomas W. Durso SEEKING STATs: Anne-Marie O’Farrell, left, and Alice Mui of DNAX found STAT5, a protein that responds to the cytokine interleukin-3. A.L.-F. Mui, H. Wakao, A.-M. O'Farrell, N. Harada, A. Miyajima, "Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs," EMBO Journal, 14:1166-75, 1995. (Cited in more than 110 publications as of April 1997) Comments by Alice L.-F. Mui, DNAX Research Institu

Listen with Speechify

0:00

3:00

Edited by: Thomas W. Durso

SEEKING STATs: Anne-Marie O’Farrell, left, and Alice Mui of DNAX found STAT5, a protein that responds to the cytokine interleukin-3.

A.L.-F. Mui, H. Wakao, A.-M. O'Farrell, N. Harada, A. Miyajima, "Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs," EMBO Journal, 14:1166-75, 1995. (Cited in more than 110 publications as of April 1997)

Comments by Alice L.-F. Mui, DNAX Research Institute of Molecular and Cellular Biology, Palo Alto, Calif.

Interleukin-3 (IL-3) is a cytokine that regulates hemopoiesis, the formation of blood cells in the body. In this paper, Alice L.-F. Mui, a senior research associate at the DNAX Research Institute of Molecular and Cellular Biology in Palo Alto, Calif., examined what happens after IL-3 binds to its receptor. "I wanted to find out what the next step in the signal-transduction cascade was," she states. "How does receptor activation lead eventually to ...

Interested in reading more?

Become a Member of

Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!

Join for free today

Already a member? Login Here