amyloid plaques

A new study links a variant of the apolipoprotein E gene called APOE ε4 to better memory in older age, even in the presence of amyloid plaques—a possible explanation for the variant’s persistence despite its association with an increased risk of Alzheimer’s disease.

The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.

Patients who received the drug fared better cognitively and functionally than those taking placebo, but still experienced losses in performance.

The test will be a cheaper and more accessible alternative to currently available diagnostic tools, researchers say.

The 58-year-old was best known for uncovering evidence of a link between pathogens and the neurodegenerative disease.

A woman whose DNA suggested she’d develop early-onset dementia staved off cognitive decline for decades.

A hormone treatment contaminated with amyloid-β given to mice caused the protein’s accumulation in their brains, suggesting the same could have occurred in humans given the therapy.

A new study reports that immune memory may contribute to neurodegenerative diseases.

The findings suggest that faster synthesis, rather than decreased clearance, causes the protein to build up in neurons.

The test uses levels of plasma amyloid-β to estimate the buildup of protein plaques in the brain.

The once fringe idea is gaining traction among the scientific community.

In a mouse model, researchers mitigated three Alzheimer’s disease–associated symptoms by stimulating gamma waves with light.

Examining the brains of seven patients who died of the prion disease called Creutzfeldt–Jakob, researchers find signs of Alzheimer’s pathology. 

Aggregate-forming amyloid β proteins are replenished more slowly with age, and this may contribute to a person's risk of developing Alzheimer’s disease.

Blocking activity of a kinase in a mouse model protects Golgi in cells and reduces the build-up of amyloid β, a primary component of Alzheimer’s disease.

Antidepressant could prevent Alzheimer’s plaques; 12,000-year-old human skeleton sequenced; disentangling the mystery of octopus arms; taking a look at the ocular microbiome

Researchers show that amyloid beta is secreted from neurons in an autophagy-dependent manner.

Researchers have been unable to reproduce findings that a cancer drug destroys amyloid beta plaques.