Video taken at the Laboratory of Pharmacology and Toxicology contract testing facility appears to show mistreatment of monkeys, dogs, and cats.

The agency plans to stop funding virtually all toxicology studies in mammals by 2035.

Machine learning could be the key to reducing the use of animals in experiments.

After the release of an undercover investigation, Corteva Agrisciences announces it will release 36 beagles for rehoming.

Scientists say that increasingly rigorous licensing procedures have complicated research efforts—and in some cases, stopped experiments completely.

A report finds a decline in the number of experiments involving animals in 2017, noting a particular decrease in procedures on dogs and primates.

Researchers develop a machine-learning tool for toxicity analyses that is more consistent in predicting chemical hazards than assays on animals.

Nearly 600 signatories, including four Nobel Prize winners, urge openness about animal experiments.

A pilot program announced last month will consider combining announced and surprise inspections.

Scientists and others have been opening their homes to research animals after the studies conclude, with legislation in some states now mandating adoption.

Transparency about the role of animals in drug development could help raise awareness of and appreciation for preclinical research.

The BMJ inquiry finds that researchers presented only select results from animal experiments when applying for funding and approval for human trials.

Experiments involving animals dropped by more than 200,000, or 5 percent, in 2016.

A new initiative in Germany aims to increase the public’s comfort with animal-based science; US government holds workshop on nonhuman primate research.

Increasingly sophisticated tissue organoids can model many aspects of disease, but animal studies retain a fundamental role in research, scientists say. 

Infusing anti-HIV antibodies provides macaques with protection against infection for up to six months, according to a study.

Regulatory and compliance expectations for animal-based research are demanding, while public and political scrutiny of animal research is rising.

Scientists debut a system that can quickly test the toxicity of thousands of compounds in vitro.

A research primate–breeding facility at the University of Oklahoma will phase out operations over the next few years.