Skip to main content

Researchers Transplant Human Neurons into Rat Brains

The human cells, engineered to respond to blue light, influenced rat behavior when stimulated.

Written byKatherine Irving
| 2 min read
a section of a rat brain is imaged in dull green. a much brighter green human organoid takes up a large portion of the left side of the brain.
Register for free to listen to this article
Listen with Speechify
0:00
2:00

For the first time, researchers have successfully transplanted human neurons into the brains of baby rats, they report today (October 12) in Nature. The human cells formed connections with rat neurons and could be used to control the rats’ behavior.

“It’s a very important . . . very cool study,” Yun Li, a molecular geneticist at the University of Toronto who was not involved in the research, tells MIT Technology Review. “The fact that they succeeded in many of these experiments is quite extraordinary.”

To perform human cell experiments, especially when studying the effects of certain drugs, scientists have developed models called organoids: tiny structures grown from stem cells that mimic the human brain or other organs. However, they can’t replicate the complexity of real human neuron development on their own, Science News reports.

In a bid to further organoid development, scientists transplanted human cerebral organoids into the brains of ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

  • A black and white headshot of Katherine Irving

    Katherine Irving is an intern at The Scientist. She studied creative writing, biology, and geology at Macalester College, where she honed her skills in journalism and podcast production and conducted research on dinosaur bones in Montana. Her work has previously been featured in Science.  

    View Full Profile

Related Topics

Related articles background image
The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

View this Issue
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad
Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

bioxcell
Scientist reviewing cellular and molecular data on a computer in a laboratory.

Building Translation-Ready Biomarkers with Connected Workflows

Danaher Logo

Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

Integra Logo
Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

Corning logo
Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
sino biological logo

Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays