drug testing

Mixtures of viruses that attack inflammatory bowel disease–causing bacteria in mice also survive the digestive tract and are well-tolerated in humans, a study finds.

The country’s provisional go-ahead could increase pressure already being exerted on the US Food and Drug Administration to approve the therapy.

A new platform enables screening a wide range of combination anticancer therapeutics in a matter of days, which may translate to personalized therapeutic regimens for patients in less time.

A Cochrane review bolsters scientists’ advice that ivermectin should not be used against the disease outside of clinical trials, while a study claiming to have found beneficial effects in patients was withdrawn following allegations of data manipulation.

Hydroxychloroquine and chloroquine, once thought to be promising COVID-19 treatments, come with serious heart risks.

Anti-doping agencies are tracking levels of various molecules in athletes’ blood and urine over time to increase their ability to detect drug misuse.

Anti-doping organizations are constantly developing new tests to catch athletes trying to boost their performance in increasingly sophisticated ways.

Fly avatars bearing multiple genetic changes akin to those of a cancer patient lead to a tailor-made treatment that has shrunk the patient’s tumors.

Researchers develop a washing method that is better at removing drugs that have contaminated hair from the outside than existing protocols.

Testing treatments on mini tumors may save time in identifying which therapies work best, a new study shows.   

What can be done to lower development costs and drug prices?

An entire industry has sprung up around resurrecting failed drugs and recycling existing compounds for novel indications.

Increasingly sophisticated tissue organoids can model many aspects of disease, but animal studies retain a fundamental role in research, scientists say. 

New insomnia drugs are coming on the market, but drug-free therapy remains the most durable treatment.

Two teams have developed tumor-implantable drug delivery devices to study real-time responses to multiple therapies in cancer patients.

A Spanish researcher faces a penalty after conducting a study for which he never obtained proper approvals or insurance.

Researchers show that lanicemine is an effective antidepressant without the adverse effects of the related hallucinogenic drug.

Results of breast cancer drug trials are regularly spun to conceal bias and make the drugs seem more effective or less toxic than they really are.