organoids

The organoids could one day be used to treat brain injuries in humans. 

By modifying a technique used to image single cells, researchers have managed to generate a super-resolution 3D image of a complete organoid in just seven seconds.

Analyzing organoids has proven slow and cumbersome for scientists. But a new technique may speed things up, producing 3D images of hundreds of organoids per hour.

The human cells, engineered to respond to blue light, influenced rat behavior when stimulated.

A single amino acid substitution in a protein causes increased neuron production in the frontal lobes of humans compared to Neanderthals—a tiny difference that could have given our species a cognitive edge, researchers say.

Disturbing circadian rhythms in organoids and mice increases intestinal tumor growth, findings that may explain a recent rise in colon cancer among young adults, the researchers behind the work say.

Controlling a growing tissue’s shape achieves deterministic and uniform patterning in intestinal organoids.

Marina Sanaki-Matsumiya figured out how to grow human somites in a dish through a process that mirrors the tissue’s development in the embryo.

The genes are involved in pacing the development of inhibitory and excitatory neurons. An imbalance in these two types of signaling is thought to play a role in autism.

A newly developed platform may one day replace cell culture and animal models to personalize cancer treatment.

Researchers are taking the concept of three-dimensional cell culture beyond single organoids to develop embryos from cells.

An unusual drug screen takes advantage of “porcupine-like” structures of cancer cells in 3D organoids.

Pradipta Ghosh has plans to revolutionize the drug discovery pipeline.