Image of tongue cancer organoids derived from a diverse pool of patients. Researchers assessed these organoids for oral cancer markers and gene expression. They also determined the chemotherapy resistance differences between the organoid samples.
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Tongue organoids help researchers identify chemoresistance drivers in tongue cancer to develop effective treatments.

organoids

Microscopy image of a 120-day old human skin organoid derived from pluripotent stem cells with tentacle-like hair follicles. The green Keratin 5 stain labels the outer layer of the follicles and the epidermis, while the red PMEL stain marks the melanocytes.

Tracking Tissue Development to Inspire Regenerative Therapies

Cross-section of striated skeletal muscle under the microscope

Carving Out a Niche for Muscle Stem Cells with 3D Culture 

Image of human fetal pancreatic organoids stained in various colors. Nuclei are stained in blue, acinar cells in green, ductal cells in white, and endocrine cells in red.

A Novel Three-in-One Pancreatic Organoid

Cluster of blue cells encasing green tube structures. 

The Era of Organoids: Disease Modeling, Developmental Research, and Drug Response Prediction 

Multicolored microscopy image of a blood generating-heart forming organoid on a black background, showing the various cell types that make up the organoid.

Scientists Get to the Heart of Blood Formation

Three-dimensional rendering of violet-colored astrocytes touching a red blood vessel.

Modeling the Blood-Brain Barrier in a Dish

Learn How 3D Cell Cultures Advance Tissue Regeneration

Organoids as a Tool for Tissue Regeneration Research 

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Transforming 3D biology using AI: Tomocube’s HT-X1™ Plus accelerates cellular and organoids label-free analysis

Studying Organ Development and Disease Using Organoids

Studying Organ Development and Disease Using Organoids

The Future of Disease Modeling for Precision Medicine

The Future of Disease Modeling for Precision Medicine

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Organoids in Space: The Next Frontier

Images of tumor organoids acquired using high-speed live cell interferometry.

Evaluating Tumor Heterogeneity with a High Throughput Pipeline

3D rendered spheroids floating on a blue background.

Developing Homogenous 3D Neural Cultures for High Throughput Screening

Gloved hand holding miniature organ models

From the Expert: Júlia Crispim da Fontoura on 3D Cell Cultures

Cartoon of a turtle inside of an ice cube.

The First Turtle Organoids

Red cells encased in cyan webbing. 

Fetal Organoids Generated From Human Amniotic Fluid

Optimizing Organoid Culture for Development and Disease Modeling

Optimizing Organoid Culture for Development and Disease Modeling

A scientist cultures organoids in a multi-well plate filled with red cell culture media

Understanding the 3D Cell Culture Revolution

An image of cells with the center stained green and some cells stained magenta over a black background.

Growing Milk-Secreting Mammary Organoids

A microplate with pink or blue solution in different wells.

High Throughput Screening Models Ramp up Lead Discovery

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Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

An illustration of mustard-colored mitochondria against a dark blue background.

Mitochondrial DNA: A Maternal Legacy That Helps Trace the Past and Diagnose the Future

Photo of a woman submerged in icy water with her head and clasped hands above water.

What are the Risks and Benefits of a Cold Plunge?

A clipboard with the word “Sepsis” written at the top, surrounded by a syringe and medications.

A Common Antidepressant Protects Organs from Damage During Sepsis

Multimedia

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
Exploring the Gut-Lung Axis in Health and Disease

Exploring the Gut-Lung Axis in Health and Disease

May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

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Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

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Characterizing Immune Memory to COVID-19 Vaccination

Characterizing Immune Memory to COVID-19 Vaccination

10X Genomics
Optimize PCR assays with true linear temperature gradients

Applied Biosystems™ VeriFlex™ System: True Temperature Control for PCR Protocols

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Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

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Latest AI software simplifies image analysis and speeds up insights for scientists

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BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

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Agilent BioTek Cytation C10 Confocal Imaging Reader

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