Sergiu Pasca Builds Brains to Study Developmental Disease
Sergiu Pasca Builds Brains to Study Developmental Disease
The Stanford University professor helped develop a technique to grow brain organoids from induced pluripotent stem cells.
Sergiu Pasca Builds Brains to Study Developmental Disease
Sergiu Pasca Builds Brains to Study Developmental Disease

The Stanford University professor helped develop a technique to grow brain organoids from induced pluripotent stem cells.

The Stanford University professor helped develop a technique to grow brain organoids from induced pluripotent stem cells.

organoids
Organoids Don’t Accurately Model Human Brain DevelopmentOrganoids Don’t Accurately Model Human Brain Development
Organoids Don’t Accurately Model Human Brain Development
Diana Kwon | Oct 23, 2019
A new study suggests that growing in a stressful environment prevents “brains-in-a-dish” from growing in the same way as their in vivo counterparts.
Image of the Day: Patient-Derived Organoids
Image of the Day: Patient-Derived Organoids
Emily Makowski | Oct 10, 2019
Three-dimensional tissue cultures grown from cancer patients’ own tumors can predict responses to the drug irinotecan.
Opinion: Develop Organoids, Not Chimeras, for Transplantation
Opinion: Develop Organoids, Not Chimeras, for Transplantation
John D. Loike and Robert Pollack | Oct 1, 2019
Scientists are devising human-animal hybrids for harvesting human organs, but lab-derived mini-organs are a less ethically fraught solution to meeting the need for transplantation.
Human Cortical Organoids Model Neuronal Networks
Human Cortical Organoids Model Neuronal Networks
Abby Olena | Aug 29, 2019
After growing in culture for a few months, the mini-brains produced rhythmic neural activity that strengthened over time.
Opinion: Develop Organoids, Not Chimeras, for Transplantation
Opinion: Develop Organoids, Not Chimeras, for Transplantation
John D. Loike, Robert Pollack | Aug 23, 2019
Scientists are devising human-animal hybrids for harvesting human organs, but lab-derived mini-organs are a less ethically fraught solution to meeting the need for transplantation.
Tumor Organoids Hold Promise for Personalizing Cancer Therapy
Tumor Organoids Hold Promise for Personalizing Cancer Therapy
Jef Akst | Jul 15, 2019
The three-dimensional cell cultures are still in the development phase, but researchers are excited about their use to predict patients’ responses to various treatment options.
Caught on Camera
Caught on Camera
The Scientist Staff | Jul 15, 2019
Selected Images of the Day from the-scientist.com
Wellcome Sanger Institute to Close Animal Facility
Wellcome Sanger Institute to Close Animal Facility
Chia-Yi Hou | Jun 10, 2019
The move reflects scientists using more cell lines and organoids in genetic research, although some experts disagree with the decision to scale back the use of animal models.
Lab-Generated Lymph Nodes Connect to Lymphatic System in Mice
Lab-Generated Lymph Nodes Connect to Lymphatic System in Mice
Ashley P. Taylor | Jun 4, 2019
Researchers hope that “lympho-organoids” could eventually treat lymphedema in humans, but the technique is currently a proof-of-concept.