Repurposed Drug Reverses Signs of Alzheimer’s in Mice, Human Cells
Repurposed Drug Reverses Signs of Alzheimer’s in Mice, Human Cells
Researchers say they hope to launch a clinical trial to test bumetanide, a diuretic approved in 2002, but how it might improve neural functioning is unclear.
Repurposed Drug Reverses Signs of Alzheimer’s in Mice, Human Cells
Repurposed Drug Reverses Signs of Alzheimer’s in Mice, Human Cells

Researchers say they hope to launch a clinical trial to test bumetanide, a diuretic approved in 2002, but how it might improve neural functioning is unclear.

Researchers say they hope to launch a clinical trial to test bumetanide, a diuretic approved in 2002, but how it might improve neural functioning is unclear.

APOE
Alzheimer’s Risk Gene Paradoxically Protects Against Memory Loss
Alzheimer’s Risk Gene Paradoxically Protects Against Memory Loss
Chloe Tenn | Oct 8, 2021
A new study links a variant of the apolipoprotein E gene called APOE ε4 to better memory in older age, even in the presence of amyloid plaques—a possible explanation for the variant’s persistence despite its association with an increased risk of Alzheimer’s disease.
Alzheimer’s Gene Linked to Higher Risk of Severe COVID-19
Alzheimer’s Gene Linked to Higher Risk of Severe COVID-19
Jef Akst | May 26, 2020
Two copies of the APOE4 variant, which confers a higher risk of dementia, doubles the risk of severe symptoms as a result of infection with SARS-CoV-2, according to a study.
Genetic Risk for Alzheimer’s Disease Linked to Highly Active Brains
Genetic Risk for Alzheimer’s Disease Linked to Highly Active Brains
Diana Kwon | Oct 1, 2019
A growing body of evidence supports the theory that neural hyperactivity and hyperconnectivity precede the pathological changes that lead to neurodegeneration.
Alzheimer’s Gene Affects Energy Consumption in Mouse Brains
Alzheimer’s Gene Affects Energy Consumption in Mouse Brains
Sukanya Charuchandra | Oct 1, 2018
One variant limited the brain’s ability to use glucose.
Fingerprints of Ongoing Human Evolution Found
Fingerprints of Ongoing Human Evolution Found
Shawna Williams | Sep 5, 2017
Genetic variants in Alzheimer’s- and smoking-related genes appear to be under selection pressure, according to a study comparing the genomes of old and young participants.
Influential Alzheimer’s Researcher Dies
Influential Alzheimer’s Researcher Dies
Jef Akst | Oct 6, 2016
Allen Roses, a professor of neurobiology at Duke University School of Medicine, has passed away at age 73.