apoptosis

Self-inflicted DNA breaks let the cells hit pause on repair of radiation-induced DNA damage, giving them time to recover, an in vitro study shows.

In vitro and mouse experiments show how cancer cells forced through tiny pores—mimicking the physical experience of metastasis—resisted programmed cell death and avoided detection by the immune cells that would normally kill them.

A new study reports that human colon cancer cells at imminent risk of death can instead develop characteristics needed to colonize new parts of the body.

Using a transgenic fruit fly model, researchers demonstrate how epithelial barriers are maintained in living organisms despite high levels of cell turnover and death.

Researchers develop a caspase inhibitor that only works after being irradiated with UV light, giving them control over apoptosis in human cells.

A new inhibitor gives researchers the ability to control programmed cell death in cultured human T cells.

The Yale neuroscientist seeks to understand the brain’s architecture and function using C. elegans.

Introducing either necroptotic cells or an enzyme that triggers necroptosis can wipe out cancer.

Telomeres in cancer cells exposed to oxidative stress got shorter and stickier.

When hair follicle stem cells lose their protein-based death cue, they take on a new role helping to repair wounds in skin.

Internalizing the environment might be the next step in humans’ relationship with our planet.

Apoptosis and other types of programmed cell death appear to be reversible.

Molecular programs can rescue cells already engaged in the process of apoptosis or other forms of programmed cell death.

The biologist earned a Nobel Prize in 2002 for his work on C. elegans.

M proteins from Streptococcus bacteria selectively kill mouse macrophages and human macrophage-like cells by prompting cell death.

The immune cells—known for clearing dead cells—also chew up live progenitors in neurogenic regions of mouse brains. 

A decade of research on intercellular mitochondrial transfer has answered some long-standing questions and raised new ones.