A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.
The immunizations are designed to target the latest Omicron subvariants, and are only authorized for people who have already received their primary vaccinations.
Studies show that a fourth mRNA vaccine dose offers the elderly and other high-risk groups strong protection against hospitalization and death from COVID-19, but experts say benefits for other populations may be more limited.
Alejandra Manjarrez, PhD | May 6, 2022 | 4 min read
Compared to mice who got the doses in separate limbs, animals receiving flu shots in the same paw for both a first and second dose had better-trained memory B cells that bound tighter to the vaccine antigen.