germinal center inside a lymph node
Booster Is Best in the Same Limb as Initial Vaccine: Mouse Study
Compared to mice who got the doses in separate limbs, animals receiving flu shots in the same paw for both a first and second dose had better-trained memory B cells that bound tighter to the vaccine antigen.
Booster Is Best in the Same Limb as Initial Vaccine: Mouse Study
Booster Is Best in the Same Limb as Initial Vaccine: Mouse Study

Compared to mice who got the doses in separate limbs, animals receiving flu shots in the same paw for both a first and second dose had better-trained memory B cells that bound tighter to the vaccine antigen.

Compared to mice who got the doses in separate limbs, animals receiving flu shots in the same paw for both a first and second dose had better-trained memory B cells that bound tighter to the vaccine antigen.

booster
People waiting in line for COVID Vaccine
CDC: COVID-19 Booster Effectiveness Wanes After Four Months
Natalia Mesa | Feb 14, 2022

The agency also finds that third shots prevented hospitalizations during the Omicron wave.


Updated Mar 8
A healthcare worker holds up three syringes with clear medicine
To Booster or Not: Scientists and Regulators Debate
Jef Akst | Sep 16, 2021
President Biden’s planned rollout of additional COVID-19 vaccine doses is set to begin next week, but questions remain about who should get them.