health care provider standing in front of gynecology stirrups holding swabs for Pap smear
DNA Methylation Could Predict Ovarian, Breast Cancers
A pair of new studies finds that analyzing material from a Pap smear can reveal tumor risk in distant parts of the body, potentially allowing early interventions.
ABOVE: © ISTOCK.COM, ANASTAS_
DNA Methylation Could Predict Ovarian, Breast Cancers
DNA Methylation Could Predict Ovarian, Breast Cancers

A pair of new studies finds that analyzing material from a Pap smear can reveal tumor risk in distant parts of the body, potentially allowing early interventions.

A pair of new studies finds that analyzing material from a Pap smear can reveal tumor risk in distant parts of the body, potentially allowing early interventions.

ABOVE: © ISTOCK.COM, ANASTAS_

BRCA2

buccal swab brca brca1 brca2 genetic test cancer screening uspstf
New Guidelines Expand BRCA Screening
Ashley P. Taylor | Aug 21, 2019
US Preventive Services Task Force recommends genetic testing for mutations in the cancer-related genes for more—but not all—women.
MyHeritage Launches Health-Related Genetic Test, Ignites Debate
Catherine Offord | Jul 9, 2019
Its screen for selected variants of some disease-linked genes gives customers an incomplete picture of their risk—do they know?
Human DNA stock photo
Setting Better Traps for PARP Inhibitors
The Scientist Creative Services Team, BPS Bioscience | Apr 19, 2022
An innovative assay permits researchers to screen for small molecule PARP inhibitors that trap the enzyme on DNA and selectively execute cancer cells.
march 2019 the scientist profile
Master Decoder: A Profile of Kári Stefánsson
Anna Azvolinsky | Mar 1, 2019
A neurologist by training, Stefánsson founded Iceland-based deCODE Genetics to explore what the human genome can tell us about disease and our species’ evolution.
PARP Inhibitors Are Improving the Outlook of Hard-to-Treat Cancers
Vicki Brower | Apr 1, 2018
With three recent FDA approvals, and a number of Phase 3 trials ongoing, the drugs are seeing a surge in interest.
First Direct-to-Consumer BRCA Test Authorized by FDA
Kerry Grens | Mar 6, 2018
The agency gave personal genomics company 23andMe the green light to screen samples for breast cancer–related genetic mutations.
Genetic Risk Factors for Breast Cancer Identified
Ashley P. Taylor | Oct 23, 2017
Researchers identify 72 novel genetic variants associated with breast cancer risk.
Q&A: Sequencing Newborns
Tracy Vence | Oct 21, 2016
Members of the BabySeq Project discuss trial enrollment, preliminary findings.
BRCA Breakthroughs?
Jenny Rood | Apr 21, 2015
Color Genomics announces a new, lower-cost BRCA mutation test, while Inserm and Quest Diagnostics reveal plans to pool patient data to investigate rare mutations.
BRCA Mutations Mapped
Tracy Vence | Apr 7, 2015
In a large study, researchers find evidence to suggest that the type and location of a woman’s BRCA1/2 mutations may affect her cancer risk.
Yet Another Lawsuit over Genetic Tests
Tracy Vence | Jun 17, 2014
Myriad Genetics, the company originally behind tests for the cancer-associated BRCA mutations, is suing another competitor for patent infringement.
Speaking of Science
The Scientist Staff | Aug 1, 2013
August 2013's selection of notable quotes
Another Lawsuit over Genetic Tests
Kate Yandell | Jul 11, 2013
Myriad Genetics, the company originally behind tests for the cancer-associated BRCA mutations, is suing two competitors for patent infringement.
Gene Patents Decision: Everybody Wins
Jeffrey M. Perkel | Jun 18, 2013
Last week’s Supreme Court decision to invalidate patents on human genes was a win for patients, independent researchers, and even the wider biotech industry.
Supreme Court Nixes Patenting Human Genes
Dan Cossins | Jun 13, 2013
The Justices have decided that isolated sequences of human DNA are not eligible for patent protection, but rules that artificial sequences can be patented.
 
Why Women’s Eggs Don’t Last
Kate Yandell | Feb 13, 2013
As reproductive tissues age, DNA repair mechanisms become less efficient, causing genomic damage to accumulate.
Should Human Genes be Patented?
Edyta Zielinska | Dec 3, 2012
The Supreme Court agrees to hear a case deciding if two cancer genes should continue to be protected by patent.
Court Rules Gene Patents Valid
Cristina Luiggi | Aug 17, 2012
Myriad Genetics can hold patents on the BRAC1 and BRAC2 oncogenes, but not on tests comparing DNA sequences.
Gene Patents Back in Court
Cristina Luiggi | Jun 19, 2012
A public interest legal group has renewed the fight against DNA patenting.