Conceptual image showing fragmented X chromosomes
How Chaos in Chromosomes Helps Drive Cancer Spread
A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.
How Chaos in Chromosomes Helps Drive Cancer Spread
How Chaos in Chromosomes Helps Drive Cancer Spread

A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.

A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.

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cGAS-STING
Infographic showing how bursting micronuclei promote cancer
Infographic: Chromosome Errors Cause Micronuclei and Drive Cancer
Samuel F. Bakhoum | Mar 1, 2022
When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.
Novel DNA-Sensing Pathway Found in Human Cells, Absent in Mice
Catherine Offord | Jan 24, 2020
This previously unknown mechanism for spotting foreign genetic material in the cytoplasm launches antiviral defenses even when the well-known immune mediator STING is absent.