colon cancer

Microbes designed to produce specific immunomodulatory metabolites could give immunotherapy a boost.

A new study reports that human colon cancer cells at imminent risk of death can instead develop characteristics needed to colonize new parts of the body.

A study finds some E. coli can deploy a chemical called colibactin to reawaken long-dormant viruses inside bacteria, causing destruction.

When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.

A study finds similarities between cells that heal wounds and those that lead deadly cancerous invasions.

Colorectal tumor cells limit their DNA repair in response to a targeted therapy, giving them a greater chance to develop resistance to the drug.

Some experts blame our modern, sugary diet, while others think that gut microbiome changes and sedentary lifestyles may play a role. Altogether, the causes are far from clear.

Physical activity, independent of diet, shifts the composition of bacteria in the intestines, spurring researchers to search for species that might provide benefits akin to working out.

Sensors encapsulated with oral chemotherapy drugs help patients and physicians keep track of treatments.

The Creighton University researcher discovered the genetic basis of hereditary breast-ovarian cancer syndrome.

Better treatment and diagnoses have helped more people survive, but economic disparities in outcomes for some preventable cancers have gotten worse.

The treatment also curbed the growth of nearby metastases that did not receive the drug.

The bacteria also promoted the growth of human colon cancer cells in a dish.

By implanting patient- or rodent-derived mini-guts into mice, scientists can rapidly create more-accurate murine models of the disease

A cell phone–based microscope can identify mutations in tumor tissue and image products of DNA sequencing reactions.

Member, Department of Immunology, St. Jude Children’s Research Hospital. Age: 43

An open mind and collaborative spirit have taken Hans Clevers on a journey from medicine to developmental biology, gastroenterology, cancer, and stem cells.

A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.