Four pregnant women sitting in chairs
Epigenetic Changes to Placenta Correlate with Maternal Depression
An epigenome-wide association study found more than a dozen methylation changes in placental DNA that correlated with expectant mothers’ self-reports of depression and stress during their pregnancy.
ABOVE: MODIFIED FROM © ISTOCK.COM, Vladimir Kononok
Epigenetic Changes to Placenta Correlate with Maternal Depression
Epigenetic Changes to Placenta Correlate with Maternal Depression

An epigenome-wide association study found more than a dozen methylation changes in placental DNA that correlated with expectant mothers’ self-reports of depression and stress during their pregnancy.

An epigenome-wide association study found more than a dozen methylation changes in placental DNA that correlated with expectant mothers’ self-reports of depression and stress during their pregnancy.

ABOVE: MODIFIED FROM © ISTOCK.COM, Vladimir Kononok

depression

Colored Genetic Code DNA Molecule Structure stock photo
Genetic Risks for Depression Differ Between Ancestral Groups
Chloe Tenn | Oct 19, 2021
A large genome-wide association study in East Asians uncovers novel genetic links to depression, calling attention to the consequences of underrepresentation of non-European groups in genetic research data.
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How Early-Morning Light Exposure Makes Mice Less Depressed
Bianca Nogrady | Jul 22, 2021
A light-sensitive gene involved in regulating the body clock may also influence mood, mediating the effect of light.
Biomarkers on the Brain: From Sequencing to Functional Imaging
Biomarkers on the Brain: From Sequencing to Functional Imaging
The Scientist Creative Services Team | Nov 16, 2021
An expert panel will discuss biomarker development for brain disorders and considerations for their clinical use.
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Religion on the Brain
Emma Yasinski | Jul 13, 2021
Researchers in a small but growing field search for neural correlates of religiosity and spirituality.
GWAS, psychotic disorder, mood disorder, Q&A, bipolar disorder, schizophrenia, depression, sex differences
Genetic Variants Tied to Sex Differences in Psychiatric Disorders
Amanda Heidt | Mar 31, 2021
The largest study of its kind identifies single nucleotide polymorphisms with disparate effects on men’s and women’s susceptibility to conditions such as bipolar disorder and schizophrenia.
Scientific Breakthroughs with Cryogenic Electron Microscopy
The Scientist Creative Services Team, Thermo Fisher Scientific | Jun 10, 2021
Structures made via cryo-EM give researchers insights into SARS-CoV-2, HIV, neurological disorders, cancer, and more.
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Distinct Microbiome and Metabolites Linked with Depression
Rachael Moeller Gorman | Dec 9, 2020
The gastrointestinal tracts of people with major depressive disorder harbor a signature composition of viruses, bacteria, and their metabolic products, according to the most comprehensive genomic and metabolomic analysis in depression to date.
How Social Isolation Affects the Brain
Catherine Offord | Jul 13, 2020
Absence of human contact is associated with declines in cognitive function. But as the COVID-19 pandemic brings concerns about the potential harms of isolation to the fore, researchers are still hunting for concrete evidence of a causal role as well as possible mechanisms.
The Scientist Speaks Ep. 16 - At the Breaking Point: Mitochondrial Deletions and the Brain
The Scientist Creative Services Team | Mar 31, 2021
Researchers characterize large mitochondrial deletions to understand their implications in neurological disorders.
Regular Exercise Helps Patients Combat Cancer
Bente Klarlund Pedersen | Apr 1, 2020
Studies point to a role for physical activity in fighting malignancies, improving treatment outcomes, and fostering overall health in patients.
Neuroscientist Phil Haydon Sets Sail to Talk About Epilepsy
Ashley Yeager | Feb 19, 2020
After an accident as a teenager, he developed the disorder. He then studied the brain to better understand his own seizures, and now plans to sail around the world to show others with the condition how to push their limits.
Infographic: The Neurobiology of Suicidal Behavior
Catherine Offord | Jan 13, 2020
Clues about the biological mechanisms that contribute to a person’s chance of contemplating or attempting suicide
What Neurobiology Can Tell Us About Suicide
Catherine Offord | Jan 13, 2020
The biochemical mechanisms in the brain underlying suicidal behavior are beginning to come to light, and researchers hope they could one day lead to better treatment and prevention strategies.
Value of Medical Marijuana for Mental Health Questioned
Jef Akst | Oct 29, 2019
A meta-analysis of more than 80 studies from the past four decades finds weak evidence to support the use of medicinal cannabis to treat anxiety, depression, and other mental health disorders.
Deep Brain Stimulation Improves Depression Symptoms: Study
Catherine Offord | Oct 7, 2019
The effects of the therapy in a small group of  patients were long-lasting, researchers say, adding to evidence that the approach works for treatment-resistant depression.
Antidepressant Approvals Could Herald New Era in Psychiatric Drugs
Bianca Nogrady | Oct 1, 2019
The FDA has given the green light to the first major new classes of antidepressant therapies in decades, opening up new avenues for therapeutic development.
Forced-Swim Test Criticized as Uninformative, Cruel
Catherine Offord | Jul 22, 2019
Some researchers and animal rights groups are amplifying their opposition to an assay that measures how long a rodent tries to stay afloat.
Gut Microbes May Play a Role in Mental Health Disorders
Ashley Yeager | Jul 5, 2019
The gut microbiome has been linked to depression, schizophrenia, and other neurological conditions, but it’s not yet clear whether the relationship is causal.
How the Brain Changes on Ketamine: A Live Animal Study
Ruth Williams | Apr 11, 2019
The drug promotes and sustains brain cell connectivity in mice, reversing the effects of chronic stress.