The biochemical mechanisms in the brain underlying suicidal behavior are beginning to come to light, and researchers hope they could one day lead to better treatment and prevention strategies.

A meta-analysis of more than 80 studies from the past four decades finds weak evidence to support the use of medicinal cannabis to treat anxiety, depression, and other mental health disorders.

The effects of the therapy in a small group of  patients were long-lasting, researchers say, adding to evidence that the approach works for treatment-resistant depression.

The FDA has given the green light to the first major new classes of antidepressant therapies in decades, opening up new avenues for therapeutic development.

Some researchers and animal rights groups are amplifying their opposition to an assay that measures how long a rodent tries to stay afloat.

The gut microbiome has been linked to depression, schizophrenia, and other neurological conditions, but it’s not yet clear whether the relationship is causal.

The drug promotes and sustains brain cell connectivity in mice, reversing the effects of chronic stress.

The nasal spray to ease intractable depression appears on the US market after decades without novel antidepressant treatments.

The research is among the first to find the connection in humans.