embryogenesis

At the Max Planck Institute of Molecular Cell Biology and Genetics, the developmental biologist is probing the maternal-fetal interface across mammalian species.

Using stem cells and a bioreactor, researchers generated living embryos that survived for more than a week and began to develop internal organs.

The Sloan Kettering researcher used mutagenic screening to probe genes and molecular pathways, including Toll and Hedgehog, essential to development in fruit flies and mice.

A phthalate commonly found in shampoos, cosmetics, and cleaning products disrupts reproduction in worms.

With just a molecular nudge, aggregates of embryonic stem cells take shape as a “gastroloid,” bearing the genetic hallmarks and spatial organization of early development.

The finding confirms that a cluster of cells that directs the fate of other cells in the developing embryo is evolutionarily conserved across the animal kingdom.

A trio of papers provide new insight into embryo development.

New details of the molecular process by which our cells consume themselves point to therapeutic potential.

New noninvasive methods of selecting the most viable embryo could revolutionize in vitro fertilization.

Advances in light microscopy allow the mapping of cell migration during embryogenesis and capture dynamic processes at the cellular level.

Associate Professor in Molecular Cell & Developmental Biology at the University of Texas at Austin, John Wallingford, makes his living using cutting-edge microscopic techniques to watch developmental events unfold in real time.

In exploring how embryos take shape, John Wallingford has identified a key pathway involved in vertebrate development—and human disease.

Novel observations can sometimes be correct for unexpected reasons.

New evidence supports an old idea that embryos with genetic abnormalities can somehow fix themselves early in development.