A color-annotated image of the muscles in the whole body of a fruit fly.

| 3 min read

Spatial Transcriptomics Reveals New Cell Types in Flies

Molecular cartography helped scientists map mRNA localization in the muscles and brains of adult Drosophila.

An image of the tardigrade species Hypsibius exemplaris stained with fluorescent dyes. This tardigrade was stained with LysoTracker Green (cyan), TMRE (magenta), and NucBlue (green). Scale bar: 20μm

| 3 min read

Getting Creative with an Extreme Animal Model

Multicolor fluorescence concept of bright colorful circles on black background

| 5 min read

Expanding the Nuclear Imaging Spectrum

fluorescence microscopy

Lenses of a fluorescent microscope illuminate a sample on a microscope slide.

A Colorful Approach to Tracking Cellular Cargo

Niki Spahich, PhD | | 4 min read

Microscopic image of a live amoeba.

Illuminating Specimens Through Live Cell Imaging

Charlene Lancaster, PhD | | 8 min read

Charting a New Course Through the Injured Brain

Rashmi Shivni | | 4 min read

An image of neurons, astrocytes, and other glial cells acquired using fluorescence microscopy.

Troubleshooting Fluorescence Microscopy Experiments

EvidentandThe Scientist Creative Services Team | | 1 min read

Dream Big and Achieve Real-Time Single Cell Imaging Without Camera Limitations

Sort What You See

BD Biosciences | | 1 min read

Illustration of newly discovered mechanism allowing kinesin to “walk” down a microtubule. A green kinesin molecule with an attached yellow fluorophore is shown passing through a blue laser as it rotates step by step along a red and purple microtubule, fueled by blue ATP molecules that are hydrolyzed into orange ADP and phosphate groups.

High-Resolution Microscope Watches Proteins Strut Their Stuff

Holly Barker, PhD | | 3 min read

To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

Infographic: DNA Damage Viewed with Unprecedented Clarity

Amanda Heidt | | 2 min read

Broken DNA

DNA Damage Viewed with Unprecedented Clarity

Amanda Heidt | | 3 min read

Microscopic image of nerves in the eye, a pathogen, and t cells

Science Snapshot: Eye Immunity

Lisa Winter | | 1 min read

Page 1 of 5 - 51 Total Items

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Trending

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

Image of a collage with human hands working with desktop icons in a collage style.

q.e.d: An AI Tool for Smarter Manuscript Review

A team of researchers developed q.e.d, an AI-powered system designed to deliver rigorous and constructive feedback on scientific manuscripts in minutes.

An enveloped virus forms.

Where Do Viruses Come From?

Using genomics, evolutionary biologists test several hypotheses on the origin of viruses. New evidence suggests they may have emerged more times than previously thought.

A depiction of gut microbes in different colors inside the intestines.

Criticism of Autism-Gut Microbiome Research Sparks Pushback

Some scientists argued that autism-gut microbiome research is rife with conceptual and methodological flaws, from mouse to human studies. Microbiome researchers disagree.

Multimedia

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.

December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue

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Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Abstract wireframe sphere with colorful dots and connecting lines representing the complex cellular and molecular interactions within the tumor microenvironment.

Exploring the Inflammatory Tumor Microenvironment

Within the tumor microenvironment, networks of cells and molecular signals form a dynamic landscape that drives disease progression.

An image of a DNA sequencing spectrum with a radial blur filter applied.

A Comprehensive Guide to Next-Generation Sequencing

Individual NGS methods come with their own pros and cons, but automation optimization solutions exist for all NGS workflows.

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BRANDTECH® Scientific Announces Strategic Partnership with Copia Scientific to Strengthen Sales and Service of the BRAND® Liquid Handling Station (LHS)

This partnership will enable both companies to reach a broader range of customers, including those with more complex and specialized workflows

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Enter Our 2026 Top Innovations Contest

Submit a cutting-edge product or technology for the chance to be recognized as one of The Scientist’s 2026 Top Innovations.

Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

Biotium's new TyraMax™ Amplification Dyes and Kits are available with the widest selection of colors for spatial analysis

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

Ten-year Agreement to Provide a Secure, AI-enabled Forensic Laboratory Information Management System Supporting DHS Forensic, Scientific, and Testing Services