A color-annotated image of the muscles in the whole body of a fruit fly.
| 3 min read
Molecular cartography helped scientists map mRNA localization in the muscles and brains of adult Drosophila.

fluorescence microscopy

Lenses of a fluorescent microscope illuminate a sample on a microscope slide.

A Colorful Approach to Tracking Cellular Cargo

Microscopic image of a live amoeba.

Illuminating Specimens Through Live Cell Imaging

Charting a New Course Through the Injured Brain

An image of neurons, astrocytes, and other glial cells acquired using fluorescence microscopy.

Troubleshooting Fluorescence Microscopy Experiments

Dream Big and Achieve Real-Time Single Cell Imaging Without Camera Limitations

Sort What You See

Illustration of newly discovered mechanism allowing kinesin to “walk” down a microtubule. A green kinesin molecule with an attached yellow fluorophore is shown passing through a blue laser as it rotates step by step along a red and purple microtubule, fueled by blue ATP molecules that are hydrolyzed into orange ADP and phosphate groups.

High-Resolution Microscope Watches Proteins Strut Their Stuff

To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

Infographic: DNA Damage Viewed with Unprecedented Clarity

Broken DNA

DNA Damage Viewed with Unprecedented Clarity

Microscopic image of nerves in the eye, a pathogen, and t cells

Science Snapshot: Eye Immunity

Trending

An old medical illustration features the ear in the center with nerves of the head shown in yellow.

The Ear as a Therapeutic Gateway to the Vagus Nerve

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

3D illustration showing three differently colored semi-translucent cells, representing different T cell subtypes, on a black background. A purple cell is in the front on the right, a red cell is on the left, and a blue cell sits behind the red one.

T Cell Nomenclature Gets an Update

A yellow-colored frozen frog.

Freeze-Tolerant Frogs Power Organ Cryopreservation Strategies

Multimedia

Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

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Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

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Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

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