A chromosome is gradually unwinding until the DNA double helix is visible. Proteins interact with parts of the DNA. Antibodies are attached to these protein-DNA interacting regions.
| 10+ min read
Proteins interact with DNA to regulate many vital processes in cells. Nearly 40 years ago, researchers developed a way to map these molecular connections.

Foundations

X-ray crystallography of penicillin

Crystal-Clear Penicillin, 1945

In urban bathhouses in Germany and the surrounding low countries, bathhouse proprietors, known as baders, provided visitors with basic medical care. To draw blood, baders would scratch the skin before placing a heated cupping glass over the incision to extract blood and purge the body. Other tools associated with baders, including dental forceps and an amputation saw, hint at further services they provided.

Bathing Through the Ages: 1300–1848

Glass blown and sculpted model of the golden bellapple (<em>Passiflora laurifolia</em>)

Glass Menagerie, 1863–1936

Glass-blown and sculpted model of the sea anemone (<em>Phymactis florida</em>)

Slideshow: The Lifelike Glass Models of Leopold and Rudolf Blaschka

A building behind trees

Ford Foundation Sunsets Diversity Fellowships

A photo of soybean pods

The Right Chemistry, 1935

A lithograph of a woman sitting up in bed while a nurse attends to her.

Death by Nostalgia, 1688

Formed of various flowers, this personification cartoon of a female botanist, painted by George Spratt, was pasted into Allen’s copy of The English Flora.

La Botaniste, 1810–1865

In one of the only known photos of Abraham Lincoln taken on the day of the Gettysburg Address, Lincoln can be seen seated, hatless, just below and to the right of the flag. Lincoln began developing symptoms of smallpox on the train home to Washington, DC.

Presidential Pox, 1863

Photograph of drought land due to climate change

An Earthy-Smelling Substance, 1964

Photograph of a waterfall

Falling Water, Rising Rocks, 1834

A black and white photo of two sets of flowers in test tubes, one of which is wilting

Posies, Poison, and Periods, Early 1920s

Birth of Midwifery, Circa 100 CE

two black-and-white microscope images, one with a few black dots, the other with many rod-shaped bacteria

Identifying a Killer, 1895

Stamping Out Science, 1948

Bile and Potatoes, 1921

Identity Crisis, 1906

Viral Discoveries, 1929

Introducing Inoculation, 1721

Action at a Distance, Circa Early 1950s

Trending

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

Photo of a woman submerged in icy water with her head and clasped hands above water.

What are the Risks and Benefits of a Cold Plunge?

A woman eating chocolate.

Why Do Some Women Crave Chocolate Before Their Period?

An illustration of mustard-colored mitochondria against a dark blue background.

Mitochondrial DNA: A Maternal Legacy That Helps Trace the Past and Diagnose the Future

Multimedia

Graphic of silver and gold 3D spheres levitating in space

Transform Omics Workflows with Scalable Cell Prep

LevitasBio
Conceptual image of genomic analysis showing multicolored DNA base sequences depicted as the letters C, G, A, and T.

Accelerating Cancer Research Through Comprehensive Genomic Analysis

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May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
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TaqMan Probe & Assays: Unveil What's Possible Together

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Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

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Products

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Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

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Latest AI software simplifies image analysis and speeds up insights for scientists

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BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

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Agilent BioTek Cytation C10 Confocal Imaging Reader

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