A chromosome is gradually unwinding until the DNA double helix is visible. Proteins interact with parts of the DNA. Antibodies are attached to these protein-DNA interacting regions.
| 10+ min read
Discover how chromatin immunoprecipitation transformed the study of DNA-protein interactions through decades of scientific innovation.

Foundations

X-ray crystallography of penicillin

Crystal-Clear Penicillin, 1945

In urban bathhouses in Germany and the surrounding low countries, bathhouse proprietors, known as baders, provided visitors with basic medical care. To draw blood, baders would scratch the skin before placing a heated cupping glass over the incision to extract blood and purge the body. Other tools associated with baders, including dental forceps and an amputation saw, hint at further services they provided.

Bathing Through the Ages: 1300–1848

Glass blown and sculpted model of the golden bellapple (<em>Passiflora laurifolia</em>)

Glass Menagerie, 1863–1936

Glass-blown and sculpted model of the sea anemone (<em>Phymactis florida</em>)

Slideshow: The Lifelike Glass Models of Leopold and Rudolf Blaschka

A building behind trees

Ford Foundation Sunsets Diversity Fellowships

A photo of soybean pods

The Right Chemistry, 1935

A lithograph of a woman sitting up in bed while a nurse attends to her.

Death by Nostalgia, 1688

Formed of various flowers, this personification cartoon of a female botanist, painted by George Spratt, was pasted into Allen’s copy of The English Flora.

La Botaniste, 1810–1865

In one of the only known photos of Abraham Lincoln taken on the day of the Gettysburg Address, Lincoln can be seen seated, hatless, just below and to the right of the flag. Lincoln began developing symptoms of smallpox on the train home to Washington, DC.

Presidential Pox, 1863

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Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

Image of a collage with human hands working with desktop icons in a collage style.

q.e.d: An AI Tool for Smarter Manuscript Review

An enveloped virus forms.

Where Do Viruses Come From?

A brown dog stares at a spoon of peanut butter in front of its face with wide eyes.

Why Do Dogs Love Peanut Butter?

Multimedia

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Merck
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

MilliporeSigma purple logo
December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.
December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Merck
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

MilliporeSigma purple logo
Abstract wireframe sphere with colorful dots and connecting lines representing the complex cellular and molecular interactions within the tumor microenvironment.

Exploring the Inflammatory Tumor Microenvironment 

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An image of a DNA sequencing spectrum with a radial blur filter applied.

A Comprehensive Guide to Next-Generation Sequencing

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Products

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BRANDTECH® Scientific Announces Strategic Partnership with Copia Scientific to Strengthen Sales and Service of the BRAND® Liquid Handling Station (LHS) 

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Enter Our 2026 Top Innovations Contest

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Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

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LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS