Dog Study Revives Concerns About Virus Used for Gene Therapy
Dog Study Revives Concerns About Virus Used for Gene Therapy
Canines treated with an adeno-associated viral (AAV) vector showed evidence that the therapeutic DNA held within the virus can integrate into the host genome, risking the activation of oncogenes.
Dog Study Revives Concerns About Virus Used for Gene Therapy
Dog Study Revives Concerns About Virus Used for Gene Therapy

Canines treated with an adeno-associated viral (AAV) vector showed evidence that the therapeutic DNA held within the virus can integrate into the host genome, risking the activation of oncogenes.

Canines treated with an adeno-associated viral (AAV) vector showed evidence that the therapeutic DNA held within the virus can integrate into the host genome, risking the activation of oncogenes.

hemophilia
Preliminary Results Point to Success of In Vivo Gene Editing
Preliminary Results Point to Success of In Vivo Gene Editing
Carolyn Wilke | Feb 12, 2019
Two studies show signs that the introduced DNA is functioning, but it’s too early to know if patients actually benefit.
Sanofi and Celgene Spend $20 Billion in Major Biotech Acquisitions
Sanofi and Celgene Spend $20 Billion in Major Biotech Acquisitions
Katarina Zimmer | Jan 22, 2018
Pharmaceutical giant Sanofi to take over hemophilia drugmaker Biovertiv, while Celgene will buy cancer drugmaker Juno Therapeutics.
First In Vivo Human Genome Editing to Be Tested in New Clinical Trial
First In Vivo Human Genome Editing to Be Tested in New Clinical Trial
Abby Olena | May 18, 2017
Sangamo Therapeutics will use zinc finger nucleases to introduce the gene for a missing clotting factor into the livers of men with hemophilia B.
Targeting DNA
Targeting DNA
Jef Akst | May 31, 2012
After 20 years of high-profile failure, gene therapy is finally well on its way to clinical approval.
Gene Editing Treats Blood Disease
Annie Gottlieb | Jun 27, 2011
Revising a dysfunctional gene in vivo for the first time, researchers successfully restore blood clotting in hemophiliac mice.