visualization of p53 protein interacting with its inhibitors MDM2 and MDMX
p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study
New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.
p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study
p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study

New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.

New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.

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human endogenous retrovirus (HERV)

The Scientist Infographics: Editor’s Picks of 2019
Jef Akst | Dec 18, 2019
This year’s most beautiful illustrations covered topics including the molecular underpinnings of Parkinson’s disease and strategies for tracking marine organisms around the world’s oceans.
Infographic: Human Endogenous Retroviruses and Disease
Katarina Zimmer | Jan 1, 2019
Human endogenous retroviruses that colonized vertebrate DNA millions of years ago have long been dismissed as junk DNA, but researchers now know that they may play important roles in cancer, neurodegeneration, and other ailments.
Taming the Transposon Hordes
Ruth Williams | Jan 1, 2019
Researchers repurpose the CRISPR machinery to turn whole classes of transposable elements on or off.
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.