New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.

This year’s most beautiful illustrations covered topics including the molecular underpinnings of Parkinson’s disease and strategies for tracking marine organisms around the world’s oceans.

Human endogenous retroviruses that colonized vertebrate DNA millions of years ago have long been dismissed as junk DNA, but researchers now know that they may play important roles in cancer, neurodegeneration, and other ailments.

Researchers repurpose the CRISPR machinery to turn whole classes of transposable elements on or off.

Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.