Modifying patients’ own T cells to carry chimeric antigen receptors (CARs) has helped treat a handful of blood cancers with unprecedented success. But the approach has faced obstacles in being translated to solid tumors, from an immune-suppressing microenvironment to the challenge of accessing a thick mass of cells.
To better recognize and follow Alzheimer’s disease in patients, researchers are looking for markers in the blood that could signal the presence of related pathologies. The field is hopeful that better biomarkers could support the identification of patients early in their disease, which could in turn enable the discovery of treatments to stave off cognitive decline.
Vesicles that are released into the apoplast between plant cells appear to play a role in defending the organism against pathogenic fungi. Recent research has shown, for example, that exosomes can carry short interfering RNAs and fungal defense proteins from the plant host cell to the ...
