Is It Time to Rethink Parkinson’s Pathology?
Is It Time to Rethink Parkinson’s Pathology?
New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.
Is It Time to Rethink Parkinson’s Pathology?
Is It Time to Rethink Parkinson’s Pathology?

New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.

New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.

neurodegenerative diseases
Infographic: How Air Pollution Could Affect the Brain
Infographic: How Air Pollution Could Affect the Brain
Catherine Offord | Oct 1, 2019
Evidence is accumulating that breathing contaminated air might impair cognition.
Air Pollution May Damage People’s Brains
Air Pollution May Damage People’s Brains
Catherine Offord | Oct 1, 2019
Contaminants in the atmosphere appear to have harmful effects on neurodevelopment and cognitive function.
Genetic Risk for Alzheimer’s Disease Linked to Highly Active Brains
Genetic Risk for Alzheimer’s Disease Linked to Highly Active Brains
Diana Kwon | Oct 1, 2019
A growing body of evidence supports the theory that neural hyperactivity and hyperconnectivity precede the pathological changes that lead to neurodegeneration.
Could Brain Activity During Sleep Be a Biomarker for Alzheimer’s?
Could Brain Activity During Sleep Be a Biomarker for Alzheimer’s?
Ashley Yeager | Oct 1, 2019
Changes in brain waves while snoozing correlate with accumulation of tau and amyloid-β, suggesting that the neural activity disruptions could clue doctors in to early development of the disease.
Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?
Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?
Ashley Yeager | Oct 1, 2019
Damage to the lysosome, the organelle that removes excess proteins, lipids, and other materials, might be at the root of the disease.
Commensal Bacterium Reduces ALS Symptoms in Mice
Commensal Bacterium Reduces ALS Symptoms in Mice
Jef Akst | Jul 24, 2019
Boosting the levels of Akkermansia muciniphila in mouse guts slowed the progression of an ALS-like disease, while two other microbiome members were associated with more severe symptoms.
Neuroscientist Rahul Desikan Dies
Neuroscientist Rahul Desikan Dies
Kerry Grens | Jul 19, 2019
He developed an MRI-based map of the human cortex, discovered genetic risk factors for neurodegenerative diseases, and wrote about his struggles with ALS.
Pro Football Players Die at a Higher Rate than Pro Baseball Players
Pro Football Players Die at a Higher Rate than Pro Baseball Players
Jef Akst | May 28, 2019
A comparison of thousands of former athletes in the two sports finds that NFL players were more likely than MLB players to die from cardiovascular and neurodegenerative diseases, in particular.
PET Scans Reveal Elevated Tau in NFL Players’ Brains
PET Scans Reveal Elevated Tau in NFL Players’ Brains
Jef Akst | Apr 12, 2019
A study hints that it might be possible to diagnose chronic traumatic encephalopathy, a neurodegenerative disease associated with frequent head injuries, while patients are still living.