As researchers unravel the molecular machinery that links exercise and cognition, working out is emerging as a promising neurotherapy.

A proposed definition of the disease emphasizes signs of neurodegeneration and the presence of β-amyloid and tau, rather than cognitive symptoms.

The elimination of these glia in the mouse brain ameliorated the development of Parkinsonian neuropathologies induced by the pesticide toxin paraquat.  

The gene-editing tool was effective in disabling a defective gene responsible for some forms of amyotrophic lateral sclerosis. 

Upping a gene’s expression in rat brains made them better learners and normalized the activity of hundreds of other genes to resemble the brains of younger animals.

Infectious protein aggregates from the skin of human patients can cause disease in mice.

Rodent studies presented at the Society for Neuroscience meeting this week tie pathologies in the gastrointestinal tract or microbiome composition with Parkinson’s and Alzheimer’s diseases.

Researchers are piecing together the links between the gut microbiome and mental health.