A pink and blue illustration of the central nervous system, visible through a translucent outline of a human head and shoulders, zooms in to show an illustration of interconnected neurons
Specific Brain Cells Linked to Parkinson’s Disease
Research identifies 10 types of dopamine-making neurons, one of which seems to die off during the disease.
ABOVE: © ISTOCK.COM, DR_MICROBE
Specific Brain Cells Linked to Parkinson’s Disease
Specific Brain Cells Linked to Parkinson’s Disease

Research identifies 10 types of dopamine-making neurons, one of which seems to die off during the disease.

Research identifies 10 types of dopamine-making neurons, one of which seems to die off during the disease.

ABOVE: © ISTOCK.COM, DR_MICROBE

neurodegenerative diseases

Ramified cells in a lilac background
Could Vitamin Supplementation Help Alzheimer’s Patients?
Alejandra Manjarrez | Apr 11, 2022
Niacin, a form of vitamin B3 used to treat cardiovascular disease, helps immune cells in the brain fight neurodegenerative diseases such as Alzheimer’s in mice models, according to recent studies. Researchers hope that human clinical trials will swiftly follow.
Electrode array, with needle-like electrodes facing upward
Brain Implant Allows Completely Paralyzed Patient to Communicate
Natalia Mesa | Mar 24, 2022
The patient, who has ALS, is able to communicate in complete sentences by deliberately altering his brain’s activity.
Explore how scientists determine the atomic structures of protein aggregates
Revolutionizing Neurodegeneration Research with Cryo-EM
The Scientist Creative Services Team, Thermo Fisher Scientific | Feb 22, 2022
Advancements in cryo-EM technology allow researchers to develop drugs and diagnostic tools for neurodegenerative diseases.
Bespectacled man wearing black shirt with arms folded looks at camera in front of lab cabinet
Neuropathologist John Trojanowski Dies at 75
Lisa Winter | Mar 18, 2022
His work was pivotal to understanding the mechanisms of neurodegenerative diseases, particularly Alzheimer’s and Parkinson’s.
Image of brain cells showing pyramidal neurons in green, astrocytes in red, and microglia in blue
Replacing Microglia Treats Neurodegenerative Disease in Mice
Shawna Williams | Mar 17, 2022
Researchers find a way to wipe out the brain’s immune cell corps and send in new and improved versions.
Melissa Vos discusses how lipids’ good intentions become harmful in Parkinson’s Disease
The Scientist Speaks - Lipids Predict a Slippery Path Towards Parkinson’s Disease
Nele Haelterman, PhD | Dec 14, 2021
Melissa Vos discusses how lipids’ good intentions become harmful in Parkinson’s Disease.
Neuro collage
Our Favorite Neuroscience Stories of 2021
Chloe Tenn | Dec 29, 2021
From a Nobel prize and photosynthesis-powered brains to neurodegeneration research and controversy over a new Alzheimer’s drug, a look back at some of the biggest brain-related developments of the year.
Microscopic photograph of brain tissue demonstrating the characteristics of Alzheimer's disease
David Gate Probes Links Between Alzheimer’s and the Immune System
James M. Gaines | Nov 1, 2021
The Northwestern University researcher studies how adaptive immune cells influence neurodegenerative disease.
40422-lt-highqualityscreening-800x560
High-Quality Screening and Target Validation During Drug Development
The Scientist Creative Services Team in collaboration with Thermo Fisher Scientific | Oct 18, 2021
Drew Adams will discuss his work developing therapeutics that promote remyelination for neurological diseases.
An artist's rendition of an RNA molecule in light blue on a dark blue background
Same RNA Acts in Neurodegeneration and Cancer
Abby Olena | Oct 29, 2021
The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.
Illustration of neurons in white with myelin in blue
Repurposed Drug Reverses Signs of Alzheimer’s in Mice, Human Cells
Jef Akst | Oct 12, 2021
Researchers say they hope to launch a clinical trial to test bumetanide, a diuretic approved in 2002, but how it might improve neural functioning is unclear.
Mapping the Brain in 3-D
Mapping the Brain in 3-D
Nathan Ni, PhD | Oct 5, 2021
3-D brain atlases help scientists better understand brain function in physiological and pathological situations.
An illustration of a yeast cell (right) and a human neuron (left) showing the processes/features that are similar in the two
Infographic: Modeling Neurodegenerative Diseases with Yeast
Mahlon Collins | Oct 1, 2021
Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.
Brain cells with electrical firing. 3D rendering.
Microglia as Therapeutic Targets in Neurodegenerative Diseases
Sruthi S. Balakrishnan | Oct 1, 2021
Pharmaceutical companies ramp up efforts to get the brain’s immune cells to help treat Alzheimer’s disease and other conditions, but not everyone agrees the approach will be effective.
Harnessing Stem Cells to Model Neurological Disorders
The Scientist Creative Services Team | Apr 15, 2021
Photographs of the October 2021 issue's contributors
Contributors
The Scientist Staff | Oct 1, 2021
Meet some of the people featured in the October 2021 issue of The Scientist.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
The Scientist's LabTalk Podcast - Episode 2
The Scientist Creative Services Team | Oct 20, 2020
Surviving Stress: The mysteries of neuronal survival and neurodegeneration
artistic drawing of neuron filled with tau proteins
Genes for Alcohol Use Disorder and Alzheimer’s Risk Overlap: Study
Emma Yasinski | Aug 24, 2021
Genetic, transcriptomic, and epigenetic data reveal molecular mechanisms tying these disorders to each other and to immune disfunction.