Oligomannate, derived from a compound in seaweed, suppresses neural inflammation caused by gut bacteria in mice.

Endolysosome leakiness allows tau to build up in cells.

In brain samples from people with Alzheimer’s disease, the protein aggregates more strongly bound proteins involved in processing RNA, the same study finds.

Contaminants in the atmosphere appear to have harmful effects on neurodevelopment and cognitive function.

A growing body of evidence supports the theory that neural hyperactivity and hyperconnectivity precede the pathological changes that lead to neurodegeneration.

Changes in brain waves while snoozing correlate with accumulation of tau and amyloid-β, suggesting that the neural activity disruptions could clue doctors in to early development of the disease.

Patients who suffer a traumatic brain injury may exhibit abnormally abundant tau protein many years later, a new in vivo imaging technique reveals.

Mutations within the MS4A gene cluster have been linked to changes in protein levels that affect disease risk.

Using super-resolution microscopy, scientists learned how mutant tau causes a memory-related protein to clump up in mouse neurons.