Mutations within the MS4A gene cluster have been linked to changes in protein levels that affect disease risk.

Boosting the levels of Akkermansia muciniphila in mouse guts slowed the progression of an ALS-like disease, while two other microbiome members were associated with more severe symptoms.

Johns Hopkins’s Ted Dawson discusses his lab’s demonstration that misfolded α-synuclein can move from the stomach to the brain and cause physical and cognitive symptoms.

A comparison of thousands of former athletes in the two sports finds that NFL players were more likely than MLB players to die from cardiovascular and neurodegenerative diseases, in particular.

A study hints that it might be possible to diagnose chronic traumatic encephalopathy, a neurodegenerative disease associated with frequent head injuries, while patients are still living.

Exposing mice to an hour of 40-hertz stimuli every day for a week reduced levels of amyloid-β plaques and tau protein, and improved cognition.

Watch the video, which shows a duck infected with H5N1 and showing signs of Parkinson's disease, that inspired Thomas Jefferson University researcher Richard Smeyne to explore the connection between viral infection and neurodegeneration.

Pathogens can take various routes to pass the blood brain barrier and damage cells.

Scientists may need to seriously reconsider the cast-aside hypothesis that pathogens can play a part in diseases such as Alzheimer’s and Parkinson’s.