A pink and blue illustration of the central nervous system, visible through a translucent outline of a human head and shoulders, zooms in to show an illustration of interconnected neurons
Specific Brain Cells Linked to Parkinson’s Disease
Research identifies 10 types of dopamine-making neurons, one of which seems to die off during the disease.
ABOVE: © ISTOCK.COM, DR_MICROBE
Specific Brain Cells Linked to Parkinson’s Disease
Specific Brain Cells Linked to Parkinson’s Disease

Research identifies 10 types of dopamine-making neurons, one of which seems to die off during the disease.

Research identifies 10 types of dopamine-making neurons, one of which seems to die off during the disease.

ABOVE: © ISTOCK.COM, DR_MICROBE

Parkinson's disease

Photo of Ana Marija Jakšic
Ana Marija Jakšić Shapes Fruit Fly Brains
Chloe Tenn | Apr 18, 2022
The Swiss Federal Institute of Technology Lausanne evolutionary neurobiologist is using Drosophila to investigate how organisms adapt to novel environments.
Bespectacled man wearing black shirt with arms folded looks at camera in front of lab cabinet
Neuropathologist John Trojanowski Dies at 75
Lisa Winter | Mar 18, 2022
His work was pivotal to understanding the mechanisms of neurodegenerative diseases, particularly Alzheimer’s and Parkinson’s.
Stem Cell Transplant Treats Parkinson’s Disease in Monkeys
Roni Dengler, PhD | Feb 7, 2022
Personalized stem cells improved motor symptoms and depression signs in monkeys modeling Parkinson’s disease, paving the way for trials in human patients.
Translucent, red-orange organs are shown inside a person’s transparent, blue torso. One region zooms in on blue lung alveoli covered by bright orange microbes.
Bacteria in the Lungs Can Regulate Autoimmunity in Rat Brains
Dan Robitzski | Mar 17, 2022
Making specific alterations to the bacterial population in a rat’s lungs either better protects the animals against multiple sclerosis–like symptoms or makes them more vulnerable, a study finds—the first demonstration of a lung-brain axis.
An illustration of a yeast cell (right) and a human neuron (left) showing the processes/features that are similar in the two
Infographic: Modeling Neurodegenerative Diseases with Yeast
Mahlon Collins | Oct 1, 2021
Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.
Scientific Breakthroughs with Cryogenic Electron Microscopy
The Scientist Creative Services Team, Thermo Fisher Scientific | Jun 10, 2021
Structures made via cryo-EM give researchers insights into SARS-CoV-2, HIV, neurological disorders, cancer, and more.
Photographs of the October 2021 issue's contributors
Contributors
The Scientist Staff | Oct 1, 2021
Meet some of the people featured in the October 2021 issue of The Scientist.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
How Infectious Diseases Affect the Brain
The Scientist Creative Services Team | Apr 8, 2021
From a loss of taste to dementia, infectious agents cause an array of neurological symptoms.
Astrocyte-to-Neuron Method Reverses Neurodegeneration in Mice
Ruth Williams | Jun 24, 2020
The cell conversion strategy restores neurons and motor functions lost as a result of an induced Parkinson’s-like illness in the animals.
pharmacology medicine parkinson's disease dopamine l-dopa levodopa Hornykiewicz obituary
Oleh Hornykiewicz, Who Pioneered Treatment for Parkinson’s, Dies
Amanda Heidt | Jun 18, 2020
The University of Toronto and University of Vienna pharmacologist developed L-dopa, a precursor to dopamine that remains the most widely used therapy for Parkinson’s disease.
The Scientist Speaks Ep. 16 - At the Breaking Point: Mitochondrial Deletions and the Brain
The Scientist Creative Services Team | Mar 31, 2021
Researchers characterize large mitochondrial deletions to understand their implications in neurological disorders.
A Citizen Scientist Makes Her Mark in Microbiome Research
Amy Schleunes | Jun 1, 2020
The BioCollective, a company that transforms whole stool samples into microbial metadata, is developing the US’s first national microbiome reference material.
Into the Light: A Profile of Joanne Chory
Emily Makowski | Mar 1, 2020
The plant geneticist has revolutionized researchers’ understanding of how light affects plant growth and development, and is engineering plants to combat climate change.
Breaking Down Barriers
The Scientist Creative Services Team | Oct 19, 2020
Looking at the future of neurodegeneration research!
Wanted: Healthy Brains
Ashley Yeager | Feb 25, 2020
Brain banks have struggled to convince unaffected individuals to donate, hampering studies on “cognitively normal” neurodevelopment and aging.
The Scientist Infographics: Editor’s Picks of 2019
Jef Akst | Dec 18, 2019
This year’s most beautiful illustrations covered topics including the molecular underpinnings of Parkinson’s disease and strategies for tracking marine organisms around the world’s oceans.
RNAi Mechanisms in Neurodegenerative Disease Therapy
The Scientist Creative Services Team | Jun 23, 2020
Experts will explore how RNAi mechanisms can modulate gene expression for the treatment of neurodegenerative diseases and how new methods for their use are being developed. 
Is It Time to Rethink Parkinson’s Pathology?
Ashley Yeager | Oct 1, 2019
New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.