Parkinson’s Patient Transplanted with Neurons Derived from iPSCs
Ashley P. Taylor | Nov 14, 2018
This is the first time researchers have tested the use of the reprogrammed stem cells in the human brain.
Can Viruses in the Genome Cause Disease?
Can Viruses in the Genome Cause Disease?
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
How Exercise Reprograms the Brain
Ashley Yeager | Nov 1, 2018
As researchers unravel the molecular machinery that links exercise and cognition, working out is emerging as a promising neurotherapy.
Parkinson’s Disease Enzyme Implicated in More Cases Than Realized
Sukanya Charuchandra | Aug 2, 2018
Levels of active LRRK2 were high even in Parkinson’s patients without a mutation in LRRK2, suggesting that inhibitors of the protein could treat a wider patient population than expected.
Neuropharmacologist Arvid Carlsson Dies at 95
Sukanya Charuchandra | Jul 2, 2018
The Nobel laureate’s discoveries led to a treatment for Parkinson’s disease.
Copper Connections
Jim Daley | May 1, 2018
Researchers initially set out to investigate the relationship between copper homeostasis and the rare Menkes disease, but they also found links to Parkinson’s.
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Cellular Senescence in Astrocytes May Play Central Role in Parkinson’s Disease
Katarina Zimmer | Jan 24, 2018
The elimination of these glia in the mouse brain ameliorated the development of Parkinsonian neuropathologies induced by the pesticide toxin paraquat.
Pfizer to Halt Alzheimer’s and Parkinson’s Drug Research
Jim Daley | Jan 7, 2018
The company’s recent effort to find new treatments for Alzheimer’s ended in disappointment.
Optogenetic Therapies Move Closer to Clinical Use
Shawna Williams | Nov 16, 2017
With a clinical trial underway to restore vision optogenetically, researchers also see promise in using the technique to treat deafness, pain, and other conditions.