Is It Time to Rethink Parkinson’s Pathology?
Is It Time to Rethink Parkinson’s Pathology?
New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.
Is It Time to Rethink Parkinson’s Pathology?
Is It Time to Rethink Parkinson’s Pathology?

New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.

New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.

Parkinson's disease
Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?
Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?
Ashley Yeager | Oct 1, 2019
Damage to the lysosome, the organelle that removes excess proteins, lipids, and other materials, might be at the root of the disease.
Chemist Christopher Dobson Dies
Chemist Christopher Dobson Dies
Ashley Yeager | Sep 16, 2019
The University of Cambridge scholar’s research on folding proteins advanced scientists’ understanding of illnesses, such as Alzheimer’s disease, Parkinson’s disease, and type 2 diabetes.
Chemicals on the Skin Could Enable Parkinson’s Detection
Chemicals on the Skin Could Enable Parkinson’s Detection
Shawna Williams | Mar 20, 2019
Researchers teamed up with a woman with a keen sense of smell to identify telling differences between healthy people and those with the neurodegenerative disease.
Can the Flu and Other Viruses Cause Neurodegeneration?
Can the Flu and Other Viruses Cause Neurodegeneration?
Ashley Yeager | Mar 1, 2019
Scientists may need to seriously reconsider the cast-aside hypothesis that pathogens can play a part in diseases such as Alzheimer’s and Parkinson’s.
Can Viruses in the Genome Cause Disease?
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Jan 1, 2019
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
Parkinson’s Patient Transplanted with Neurons Derived from iPSCs
Parkinson’s Patient Transplanted with Neurons Derived from iPSCs
Ashley P. Taylor | Nov 14, 2018
This is the first time researchers have tested the use of the reprogrammed stem cells in the human brain.
How Exercise Reprograms the Brain
How Exercise Reprograms the Brain
Ashley Yeager | Nov 1, 2018
As researchers unravel the molecular machinery that links exercise and cognition, working out is emerging as a promising neurotherapy.
Parkinson’s Disease Enzyme Implicated in More Cases Than Realized
Parkinson’s Disease Enzyme Implicated in More Cases Than Realized
Sukanya Charuchandra | Aug 2, 2018

Levels of active LRRK2 were high even in Parkinson’s patients without a mutation in LRRK2, suggesting that inhibitors of the protein could treat a wider patient population than expected.

Neuropharmacologist Arvid Carlsson Dies at 95
Neuropharmacologist Arvid Carlsson Dies at 95
Sukanya Charuchandra | Jul 2, 2018
The Nobel laureate’s discoveries led to a treatment for Parkinson’s disease.